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Protein degraders are getting a lot of attention for being a new and promising modality to treat diseases such as cancer or Alzheimer’s disease. Rather than inhibiting the function of a protein,...

Are you struggling to tame your mischievous membrane proteins? Find out how NanoTemper can help you to characterize even the most challenging membrane protein samples. You will learn how Prometheus ca

Conferences in 2021 will gather scientists and experts eager to discuss new discoveries in the emerging field of targeted protein degradation (TPD). Many transcription factors, scaffold proteins,...

Bifunctional degrader molecules (also known as PROTACs) and molecular glues recruit proteins to E3 ubiquitin ligases. The formation of a ternary complex between PROTAC, ligase, and the protein of inte


Despite extensive efforts, neurodegenerative diseases (ND) continue to feel like a pharmaceutical frontier. We have yet to see any effective drugs for conditions such as Alzheimer’s, Parkinson’s,...


If you study neurodegenerative diseases (ND), you already know they are one of the most challenging — and fascinating — types of diseases to study. With protein aggregation being a hallmark of ND,...


