Gene Therapy
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46:44WatchThe importance of molecular interactions and stability in Gene Therapy
New advances in gene therapy have triggered a resurgence of interest in the field. Though gene therapy offers exciting potential for the treatment of both monogenic disorders as well as more genetical
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18:38WatchSolutions for gene therapy using a deeper analytical characterization of AAV vector development
Gene therapy—a type of DNA-based medicine that utilizes a virus to insert a healthy gene into cells to replace a mutated, disease-causing variant has emerged as one of the most promising medical treat
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ReadMethods Matter: Standard production platforms for recombinant AAV produce chemically and functionally distinct vectors
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ReadQuantitation of trace levels of DNA released from disrupted Adeno-associated virus gene therapy vectors
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38:40WatchPractical strategies for overcoming challenges in the development of AAV vectors for gene therapy
Gene therapy promises to treat and potentially cure a disease by correcting its underlying genetic cause. While gene therapies that utilize AAV vectors have shown encouraging results —including a few
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ReadFrancisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing
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ReadAntibody-targeted chromatin enables effective intracellular delivery and functionality of CRISPR/Cas9 expression plasmids
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ReadIntrinsic differential scanning fluorimetry for fast and easy identification of Adeno-Associated Virus serotypes
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ReadHumanized Selective CD19CAR-T Cells Treatment Shows Efficacy in B-ALL Patients Who Relapsed after Receiving Murine-Based CD19CAR-T Therapies
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ReadSpatial screening of hemagglutinin on Influenza A Virus particles: Sialyl-LacNAc displays on DNA and PEG scaffolds reveal requirements
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