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Most labs dedicated to drug discovery — in big pharma, biopharma, or CROs — make it a priority to have an adequate lineup of instruments for their screening campaigns. They decide on what...

Protein degraders are getting a lot of attention for being a new and promising modality to treat diseases such as cancer or Alzheimer’s disease. Rather than inhibiting the function of a protein,...

NanoTemper Technologies and PharmAI combine competencies to develop biophysical tools that remove costly and time-consuming guesswork from large datasets. PRESS RELEASE MUNICH, Germany, 24 March...

If you’ve ever had to pipette really small volumes, such as what is required in 384-well plates, you’re definitely familiar with the frustrations that come along with it. The concentration alone...

As the folding of a protein is intimately linked to its function, more insight into the principles behind protein folding and the correct foldedness of proteins leads to better understanding of...

Conferences in 2021 will gather scientists and experts eager to discuss new discoveries in the emerging field of targeted protein degradation (TPD). Many transcription factors, scaffold proteins,...

Any researcher looking to better understand their protein’s behavior can benefit from the information provided by Dynamic Light Scattering (DLS). Here’s an overview of DLS and how it’s useful for...

Federal grants serve as the bread and butter for funding most, if not all, academic research labs. To write grant proposals and finally submit them is no trivial task. These generally take months...

Despite extensive efforts, neurodegenerative diseases (ND) continue to feel like a pharmaceutical frontier. We have yet to see any effective drugs for conditions such as Alzheimer’s, Parkinson’s,...

A caveat to a successful pharmaceutical industry in which many effective drugs have already been discovered is the notion that the high hanging fruits left unpicked come in the form of challenging...

Biologic drugs have been incredibly successful in terms of both medical achievement and profitability. Many of these are recombinant proteins and antibodies that treat a myriad of conditions...

Take a moment to consider what it would have been like to be a researcher in your field a hundred, fifty, or even twenty years ago. The technology that enables us to make scientific progress is...

Starting your own lab is a very exciting and rewarding opportunity. And, even if you are still early in your research career but are considering becoming a PI in the future, it wouldn’t hurt to...

Starting a new lab as a principal investigator is an exhilarating endeavor. However, you’re met with an immediate challenge: you have to recruit new members to your lab. Potential members of your...

As a new principal investigator, you now have a leadership role, guiding your lab members toward a common research goal. Each team member may bring their own unique strengths and weaknesses that...

If you study neurodegenerative diseases (ND), you already know they are one of the most challenging — and fascinating — types of diseases to study. With protein aggregation being a hallmark of ND,...

Prometheus, the new gold standard, now provides clarity to the most challenging stability characterizations

Grant writing is an important bread-and-butter skill that all principal investigators must develop, as this will ensure your lab gets funded to continue conducting research. Reagents, lab member...

PRESS RELEASE South San Francisco, CA. NanoTemper Technologies, well-known for creating biophysical tools that address challenging characterizations, today announced the new Monolith, redesigned...