Blog

  • Can bioanalytical tools solve your neurodegenerative disease research challenges? 4 questions to ask yourself

    Can bioanalytical tools solve your neurodegenerative disease research challenges? 4 questions to ask yourself

    Despite extensive efforts, neurodegenerative diseases (ND) continue to feel like a pharmaceutical frontier. We have yet to see any effective drugs for conditions such as Alzheimer’s, Parkinson’s,...

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  • 3 case studies on how to characterize challenging drug discovery targets — membrane proteins, peptide libraries, and PROTACs

    3 case studies on how to characterize challenging drug discovery targets — membrane proteins, peptide libraries, and PROTACs

    A caveat to a successful pharmaceutical industry in which many effective drugs have already been discovered is the notion that the high hanging fruits left unpicked come in the form of challenging...

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  • How Amgen looks at stability characterization to boost the success of biologics candidates

    How Amgen looks at stability characterization to boost the success of biologics candidates

    Biologic drugs have been incredibly successful in terms of both medical achievement and profitability. Many of these are recombinant proteins and antibodies that treat a myriad of conditions...

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  • The NanoTemper Story – Chapter 6: The Prometheus Panta

    The NanoTemper Story – Chapter 6: The Prometheus Panta

    Take a moment to consider what it would have been like to be a researcher in your field a hundred, fifty, or even twenty years ago. The technology that enables us to make scientific progress is...

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  • What to consider before accepting an offer to start your lab

    What to consider before accepting an offer to start your lab

    Starting your own lab is a very exciting and rewarding opportunity. And, even if you are still early in your research career but are considering becoming a PI in the future, it wouldn’t hurt to...

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  • How to convince researchers to join your new lab (over more established ones)

    How to convince researchers to join your new lab (over more established ones)

    Starting a new lab as a principal investigator is an exhilarating endeavor. However, you’re met with an immediate challenge: you have to recruit new members to your lab. Potential members of your...

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  • A guide to drafting an all-star team for your lab

    A guide to drafting an all-star team for your lab

    As a new principal investigator, you now have a leadership role, guiding your lab members toward a common research goal. Each team member may bring their own unique strengths and weaknesses that...

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  • Characterize the true nature of intrinsically disordered proteins without immobilizing them

    Characterize the true nature of intrinsically disordered proteins without immobilizing them

    If you study neurodegenerative diseases (ND), you already know they are one of the most challenging — and fascinating — types of diseases to study. With protein aggregation being a hallmark of ND,...

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  • NanoTemper Technologies launches DLS capability with Prometheus Panta, bringing high-resolution, domain-specific stability characterization

    NanoTemper Technologies launches DLS capability with Prometheus Panta, bringing high-resolution, domain-specific stability characterization

    Prometheus, the new gold standard, now provides clarity to the most challenging stability characterizations

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  • Seven tips to give your grant proposal that extra edge

    Seven tips to give your grant proposal that extra edge

    Grant writing is an important bread-and-butter skill that all principal investigators must develop, as this will ensure your lab gets funded to continue conducting research. Reagents, lab member...

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  • NanoTemper debuts the newly redesigned Monolith, offering higher-quality molecular interaction measurements for very challenging targets

    NanoTemper debuts the newly redesigned Monolith, offering higher-quality molecular interaction measurements for very challenging targets

    PRESS RELEASE South San Francisco, CA. NanoTemper Technologies, well-known for creating biophysical tools that address challenging characterizations, today announced the new Monolith, redesigned...

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  • How to confirm you’ve cooked perfect eggs, using scientific instruments

    How to confirm you’ve cooked perfect eggs, using scientific instruments

    If you’ve been following my cooking and chemistry blog series, I hope you’ve enjoyed recaps of interesting lessons I learned from HarvardX’s course. For my last post in this series, I’m digging...

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  • The NanoTemper Story – Chapter 5: The Dianthus

    The NanoTemper Story – Chapter 5: The Dianthus

    Almost as soon as the Monolith launched, the handful of people that made up NanoTemper in those early days huddled around, brainstorming how to translate the technology into a well-based assay....

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  • The NanoTemper Story – Chapter 4: The Tycho

    The NanoTemper Story – Chapter 4: The Tycho

    What would you do if you created a brilliant new invention, but no one knew or understood why they would use it? You know that it would change the way everyone works and lives, but you need to...

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  • The NanoTemper Story – Chapter 3: The Prometheus

    The NanoTemper Story – Chapter 3: The Prometheus

    By 2014, NanoTemper had won a slew of awards for the Monolith. Labs throughout Europe were using MST to measure their biological interactions, and the technology was starting to catch on...

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  • The NanoTemper Story – Chapter 2: The Monolith

    The NanoTemper Story – Chapter 2: The Monolith

    It’s late at night in Munich, Germany sometime in the late 2000’s. A man huddles in a dimly lit basement, painting. He paints at night after a complaint from the professors upstairs about the...

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  • The NanoTemper Story – Chapter 1: The Founding

    The NanoTemper Story – Chapter 1: The Founding

    Think back to your childhood. When people asked you, “What do you want to be when you grow up?” what was your response? At a guess, if everyone did what they said they planned at age four, we’d...

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  • 4 SPR assay problems that can be resolved by improving protein quality

    4 SPR assay problems that can be resolved by improving protein quality

    Surely you’ve found yourself in a research situation where your experimental results left you scratching your head. Any type of lab work will sometimes do that to you, and Surface Plasmon...

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  • NanoTemper opens tech-forward demo facility in Japan showcasing new technology and offering hands-on experience

    NanoTemper opens tech-forward demo facility in Japan showcasing new technology and offering hands-on experience

    Centrally located in the brand-new, swanky Minato Mirai Centre building in Yokohama Minato Mirai, Japan is NanoTemper Technologies’ newest tech-forward demo facility. Opened to support our...

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  • What makes chocolate silky, smooth, and crunchy all at the same time!

    What makes chocolate silky, smooth, and crunchy all at the same time!

    In this six-part blog series, I’ll share interesting and practical cooking insights that I learned from HarvardX’s Science & Cooking: From Haute Cuisine to Soft Matter Science (chemistry). I’m a...

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