Blog

  • How to look at your protein’s functionality and concentration with Tycho.Cloud

    How to look at your protein’s functionality and concentration with Tycho.Cloud

    Whether you’re a Tycho.Cloud user or just hearing about it, the big vision for Tycho.Cloud and its current capabilities are focused on helping you get more out of your Tycho data and really...

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  • Become an expert in analyzing your Prometheus data in the PR.Stability Analysis software

    Become an expert in analyzing your Prometheus data in the PR.Stability Analysis software

    Anyone who has ever worked in a lab has heard the same refrain in some context or another – “We need more data!” No matter how many experiments you do, it feels like reviewers, regulators, or even...

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  • Chemistry & cooking series: Why pancakes bubble

    Chemistry & cooking series: Why pancakes bubble

    In this six-part blog series, I’ll share interesting and practical cooking insights that I learned from HarvardX’s Science & Cooking: From Haute Cuisine to Soft Matter Science (chemistry). I’m a...

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  • What these 3 publications uncovered about coronavirus protein structures using MST

    What these 3 publications uncovered about coronavirus protein structures using MST

    Coronaviruses (CoV) have been responsible for multiple outbreaks this century. The 2020 COVID-19 pandemic — caused by the novel SARS-CoV-2 coronavirus — has led to a global health, social, and...

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  • How to get the most out of your merged data set in PR. Stability Analysis

    How to get the most out of your merged data set in PR. Stability Analysis

    Here’s a scenario that’s all too familiar to many researchers: you’ve spent weeks, maybe months, in the lab. You’ve designed experiments – made mutations, engineered cell lines, optimized...

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  • What I learned from a science and cooking course, starting with making perfect french fries!

    What I learned from a science and cooking course, starting with making perfect french fries!

    Who would have thought that a few months ago we’d be spending entire weeks at home with orders to shelter-in-place? For many, it’s been an opportunity to try things you’ve always wanted to do, and...

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  • 3 Tycho.Cloud apps that help you compare protein samples

    3 Tycho.Cloud apps that help you compare protein samples

    Tycho gives you a better idea of what you’re working with by comparing your samples: Comparing a protein before and after storage, or comparing a protein in different buffers, or comparing the...

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  • These 7 key proteins may hold the key to effective therapies for neurodegenerative diseases

    These 7 key proteins may hold the key to effective therapies for neurodegenerative diseases

    Despite the vast differences in symptoms experienced by patients with neurodegenerative diseases (ND), their pathology shares similar features at a molecular level. Most notably, many ND involve...

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  • How the cloud will transform the way you do research

    How the cloud will transform the way you do research

    Imagine how your scientific research can be made easier Imagine this scenario: you run a binding affinity assay on, let’s say, NanoTemper’s Monolith, and instead of just a Kd result, you get...

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  • How to navigate your Prometheus data in PR.Stability Analysis software

    How to navigate your Prometheus data in PR.Stability Analysis software

    One of the challenges many scientists face is how to best present their data. No matter how stunning and ground-breaking your conclusions are, you’re not going to convince anyone your hypothesis...

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  • Qualify for a free Tycho and join the 1001 Protein Challenge

    Qualify for a free Tycho and join the 1001 Protein Challenge

    Nature survey shows there’s a reproducibility crisis After Nature published a survey of 1576 researchers, it became clear that the life science research community is facing a reproducibility...

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  • 8 science podcasts we’re binge listening to and learning from

    8 science podcasts we’re binge listening to and learning from

    In Germany, we have a saying: “Mir fällt die Decke auf den Kopf,” which loosely translates to “the ceiling is falling on my head.” It describes feeling stir-crazy that results from spending too...

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  • 10 ways to fund your neurodegenerative disease research (that aren’t just the government)

    10 ways to fund your neurodegenerative disease research (that aren’t just the government)

    Neurodegenerative diseases (ND) are already taking a huge toll on the aging world population. Alzheimer’s disease, in particular, impacts more than 5 million Americans, and The Harvard...

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  • Why the first step in effective analytical characterization of biologics should be knowing stability

    Why the first step in effective analytical characterization of biologics should be knowing stability

    Successful characterization of any biologic should start by first monitoring stability as it is closely linked to its functional activity. Also, stability plays a key role in determining the...

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  • 3 biggest challenges in neurodegenerative disease research and why you should focus on them

    3 biggest challenges in neurodegenerative disease research and why you should focus on them

    Neurodegenerative diseases (ND) are very complex disorders. Not only is each one different, displaying unique combinations of symptoms and progressing at varying rates, but the biochemical...

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  • The 6 parameters you should know to understand protein stability

    The 6 parameters you should know to understand protein stability

    To understand a given protein’s stability is to gain insight into its structure and its function. Light changes to protein architecture or its environment can significantly alter its biological...

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  • 5 publications that put protein quality checks into the workflow, using Tycho

    5 publications that put protein quality checks into the workflow, using Tycho

    Tycho launched a little over two years ago in January 2018 as the solution for quickly assessing protein quality. Soon after, The Scientist journal even recognized Tycho as one of the top 10...

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  • 3 big takeaways from Festival of Biologics and the future of biotherapeutics development

    3 big takeaways from Festival of Biologics and the future of biotherapeutics development

    Festival of Biologics was an eventful gathering of leading researchers, clinicians, and regulatory agents brought together in San Diego to discuss the latest antibody and biosimilars discovery and...

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  • How characterizing molecular interactions gives biologists a different perspective on cellular processes

    How characterizing molecular interactions gives biologists a different perspective on cellular processes

    Studying cells from the perspective of a physicist might sound a little confusing for many biologists. However, the laws of physics apply to all things — including biological systems — and provide...

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  • How to find out if your protein unfolding or aggregation is reversible

    How to find out if your protein unfolding or aggregation is reversible

    During production, purification, formulation, and storage processes, proteins are often exposed to a variety of physical and chemical stresses that can cause them to unfold, aggregate, and...

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