Blog

Anyone who has ever worked in a lab has heard the same refrain in some context or another – “We need more data!” No matter how many experiments you do, it feels like reviewers, regulators, or even...

In this six-part blog series, I’ll share interesting and practical cooking insights that I learned from HarvardX’s Science & Cooking: From Haute Cuisine to Soft Matter Science (chemistry). I’m a...

Coronaviruses (CoV) have been responsible for multiple outbreaks this century. The 2020 COVID-19 pandemic — caused by the novel SARS-CoV-2 coronavirus — has led to a global health, social, and...

Here’s a scenario that’s all too familiar to many researchers: you’ve spent weeks, maybe months, in the lab. You’ve designed experiments – made mutations, engineered cell lines, optimized...

Who would have thought that a few months ago we’d be spending entire weeks at home with orders to shelter-in-place? For many, it’s been an opportunity to try things you’ve always wanted to do, and...

Tycho gives you a better idea of what you’re working with by comparing your samples: Comparing a protein before and after storage, or comparing a protein in different buffers, or comparing the...

Despite the vast differences in symptoms experienced by patients with neurodegenerative diseases (ND), their pathology shares similar features at a molecular level. Most notably, many ND involve...

Imagine how your scientific research can be made easier Imagine this scenario: you run a binding affinity assay on, let’s say, NanoTemper’s Monolith, and instead of just a Kd result, you get...

One of the challenges many scientists face is how to best present their data. No matter how stunning and ground-breaking your conclusions are, you’re not going to convince anyone your hypothesis...

Nature survey shows there’s a reproducibility crisis After Nature published a survey of 1576 researchers, it became clear that the life science research community is facing a reproducibility...

In Germany, we have a saying: “Mir fällt die Decke auf den Kopf,” which loosely translates to “the ceiling is falling on my head.” It describes feeling stir-crazy that results from spending too...

Neurodegenerative diseases (ND) are already taking a huge toll on the aging world population. Alzheimer’s disease, in particular, impacts more than 5 million Americans, and The Harvard...

Successful characterization of any biologic should start by first monitoring stability as it is closely linked to its functional activity. Also, stability plays a key role in determining the...

Neurodegenerative diseases (ND) are very complex disorders. Not only is each one different, displaying unique combinations of symptoms and progressing at varying rates, but the biochemical...

To understand a given protein’s stability is to gain insight into its structure and its function. Light changes to protein architecture or its environment can significantly alter its biological...

Tycho launched a little over two years ago in January 2018 as the solution for quickly assessing protein quality. Soon after, The Scientist journal even recognized Tycho as one of the top 10...

Festival of Biologics was an eventful gathering of leading researchers, clinicians, and regulatory agents brought together in San Diego to discuss the latest antibody and biosimilars discovery and...

Studying cells from the perspective of a physicist might sound a little confusing for many biologists. However, the laws of physics apply to all things — including biological systems — and provide...

During production, purification, formulation, and storage processes, proteins are often exposed to a variety of physical and chemical stresses that can cause them to unfold, aggregate, and...