Monolith Publications

  • A small compound targeting prohibitin with potential interest for cognitive deficit rescue in aging mice and tau pathology treatment

    A small compound targeting prohibitin with potential interest for cognitive deficit rescue in aging mice and tau pathology treatment

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  • An engineered monomer binding-protein for alpha-syn efficiently inhibits the proliferation of amyloid fibrils

    An engineered monomer binding-protein for alpha-syn efficiently inhibits the proliferation of amyloid fibrils

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  • Prolyl oligopeptidase enhances alpha-syn dimerization

    Prolyl oligopeptidase enhances alpha-syn dimerization

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  • Rescue of cognitive deficits in APP/PS1 mice by accelerating the aggregation of ß-amyloid peptide

    Rescue of cognitive deficits in APP/PS1 mice by accelerating the aggregation of ß-amyloid peptide

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  • Structural basis of small molecule targetability of monomeric tau protein

    Structural basis of small molecule targetability of monomeric tau protein

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  • Elongator mutation in mice induces neurodegeneration and ataxia-like behavior

    Elongator mutation in mice induces neurodegeneration and ataxia-like behavior

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  • Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice

    Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice

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  • The ACT domain in chloroplast precursor–phosphorylating STY kinases binds metabolites and allosterically regulates kinase activity

    The ACT domain in chloroplast precursor–phosphorylating STY kinases binds metabolites and allosterically regulates kinase activity

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  • Trehalose 6-phosphate positively regulates fatty acid synthesis by stabilizing WRINKLED1

    Trehalose 6-phosphate positively regulates fatty acid synthesis by stabilizing WRINKLED1

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  • Recognition motif and mechanism of ripening inhibitory peptides in plant hormone receptor ETR1

    Recognition motif and mechanism of ripening inhibitory peptides in plant hormone receptor ETR1

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  • Receptor kinase THESEUS1 is a rapid alkalinization factor 34 receptor in Arabidopsis

    Receptor kinase THESEUS1 is a rapid alkalinization factor 34 receptor in Arabidopsis

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  • A novel anti-platelet aggregation target of chinensinaphthol methyl ether and neojusticin B obtained from Rostellularia procumbens (L.) Nees

    A novel anti-platelet aggregation target of chinensinaphthol methyl ether and neojusticin B obtained from Rostellularia procumbens (L.) Nees

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  • New natural inhibitors of hexokinase 2 (HK2): Steroids from Ganoderma sinense

    New natural inhibitors of hexokinase 2 (HK2): Steroids from Ganoderma sinense

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  • Reciprocal regulation of the TOR Kinase and ABA receptor balances plant growth and stress response

    Reciprocal regulation of the TOR Kinase and ABA receptor balances plant growth and stress response

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  • Ningnanmycin inhibits tobacco mosaic virus virulence by binding directly to its coat protein discs

    Ningnanmycin inhibits tobacco mosaic virus virulence by binding directly to its coat protein discs

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  • Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site

    Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site

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  • An evaluation assay for thymine–mercuric–thymine coordination in the molecular beacon-binding system based on microscale thermophoresis

    An evaluation assay for thymine–mercuric–thymine coordination in the molecular beacon-binding system based on microscale thermophoresis

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  • PD-1/PD-L1 binding studies using microscale thermophoresis

    PD-1/PD-L1 binding studies using microscale thermophoresis

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  • Fragment-based approach to identify IDO1 inhibitor building blocks

    Fragment-based approach to identify IDO1 inhibitor building blocks

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  • The molecular basis of phosphite and hypophosphite recognition by ABC-transporters

    The molecular basis of phosphite and hypophosphite recognition by ABC-transporters

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