Monolith Publications

  • Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site

    Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site

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  • Near-native, site-specific and purification-free protein labeling for quantitative protein interaction analysis by MicroScale Thermophoresis

    Near-native, site-specific and purification-free protein labeling for quantitative protein interaction analysis by MicroScale Thermophoresis

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  • PD-1/PD-L1 binding studies using microscale thermophoresis

    PD-1/PD-L1 binding studies using microscale thermophoresis

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  • Fragment-based approach to identify IDO1 inhibitor building blocks

    Fragment-based approach to identify IDO1 inhibitor building blocks

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  • An evaluation assay for thymine–mercuric–thymine coordination in the molecular beacon-binding system based on microscale thermophoresis

    An evaluation assay for thymine–mercuric–thymine coordination in the molecular beacon-binding system based on microscale thermophoresis

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  • The molecular basis of phosphite and hypophosphite recognition by ABC-transporters

    The molecular basis of phosphite and hypophosphite recognition by ABC-transporters

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  • The molecular basis of phosphite and hypophosphite recognition by ABC-transporters

    The molecular basis of phosphite and hypophosphite recognition by ABC-transporters

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  • Structural basis of arrestin-3 activation and signaling

    Structural basis of arrestin-3 activation and signaling

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  • Microscale Thermophoresis in drug discovery

    Microscale Thermophoresis in drug discovery

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  • Ubiquitin linkage-specific affimers reveal Insights into K6-linked ubiquitin signaling

    Ubiquitin linkage-specific affimers reveal Insights into K6-linked ubiquitin signaling

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  • Stereotyped antibody responses target posttranslationally modified gluten in celiac disease

    Stereotyped antibody responses target posttranslationally modified gluten in celiac disease

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  • Structural determinants of 5′,6′-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel

    Structural determinants of 5′,6′-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel

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  • Phosphorylation of human aquaporin 2 (AQP2) allosterically controls its interaction with the lysosomal trafficking protein LIP5

    Phosphorylation of human aquaporin 2 (AQP2) allosterically controls its interaction with the lysosomal trafficking protein LIP5

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  • Biophysical analysis of arabidopsis protein-only RNase P alone and in complex with tRNA provides a refined model of tRNA binding

    Biophysical analysis of arabidopsis protein-only RNase P alone and in complex with tRNA provides a refined model of tRNA binding

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  • Aptatope mapping of the binding site of a progesterone aptamer on the steroid ring structure

    Aptatope mapping of the binding site of a progesterone aptamer on the steroid ring structure

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  • Detection and characterization of small molecule interactions with fibrillar protein aggregates using Microscale Thermophoresis

    Detection and characterization of small molecule interactions with fibrillar protein aggregates using Microscale Thermophoresis

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  • Structural basis of egg coat-sperm recognition at fertilization

    Structural basis of egg coat-sperm recognition at fertilization

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  • Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy

    Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy

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  • The monoclonal S9.6 antibody exhibits highly variable binding affinities towards different R-loop sequences

    The monoclonal S9.6 antibody exhibits highly variable binding affinities towards different R-loop sequences

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  • New peptide inhibitors modulate the self-assembly of islet amyloid polypeptide residues 11–20 in vitro

    New peptide inhibitors modulate the self-assembly of islet amyloid polypeptide residues 11–20 in vitro

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