Prometheus | Protein Stability + Aggregation + Particle Sizing
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The new gold standard for challenging stability characterizations brings DLS to your biologics workflow
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2:46WatchPrometheus Panta adds DLS to the new gold standard for challenging stability characterization
Learn what attributes Prometheus users considered a must-have and how we made sure to preserve them when integrating and implementing new biophysical techniques. Prometheus Panta gives you the ability
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Prometheus, the new gold standard for challenging stability characterizations
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The definitive guide to understanding protein stability
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2:09WatchAutomate your screening workflow for characterizing protein stability
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Ready to tackle your challenging stability characterizations?
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Use of self-interaction parameters derived from light scattering experiments for better developability assessment of biologic therapeutics
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The biologics researcher's guide to DLS
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25:08WatchOvercome bottlenecks in viral vector manufacturing
The success of your gene therapy vectors is dependent on optimal formulation conditions. Finding a buffer that provides better long-term stability for AAVs is a crucial step in the process of developi
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Stability optimization of engineered mAbs
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ReadHow do you get reproducible data from protein characterization experiments? Try following this DIN SPEC
Reproducibility is a key tenet of scientific research, but many pharma groups have projects that collaborate across different sites or that rely on materials prepared by other specialist...
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34:16WatchDLS easily explained: What it tells you about your protein
Join this webinar to learn about the physical phenomenon that drives Dynamic Light Scattering (DLS), and see a few examples of how DLS gives you deeper insights.
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21:48WatchHow to improve outcomes of your viral vectors for gene therapy with high-quality data from biophysical profiling methods
Optimizing your vectors for gene therapy is a daunting task. When developing and optimizing AAVs, concerns such as serotype, storage stability, expression method, and genetic fill level must be addres
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ReadStepwise conformational stabilization of a HIV-1 clade C consensus envelope trimer immunogen impacts vaccine-induced antibody responses
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Analyze self-interaction to predict viscosity and aggregation propensity at higher concentrations
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ReadAn application of nano differential scanning fluorimetry for higher order structure assessment between mAb originator and biosimilars
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25:16WatchThe autocorrelation function: the key to understanding your biological molecules
Dynamic Light Scattering (DLS) is a technique that allows researchers to accurately size their biologic molecules and determine the distribution of particle sizes in a solution. In order to turn scatt
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18:48WatchMulti-parameter formulation development for an HIV-vaccine protein with direct validation of epitope binding
Join Thomas Schubert, CEO of 2bind, as he walks through experiments done on the Prometheus Panta to determine the optimal buffer for a vaccine candidate.
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ReadRapid development of SARS-CoV-2 spike protein receptor-binding domain self-assembled nanoparticle vaccine candidates
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Sizing accuracy and intra-assay precision of DLS measurements with Prometheus Panta
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28:21WatchUse of high-throughput methods for early stage formulation evaluation and their correlation to stability studies
AbbVie preformulation is an early discovery biologics group working to optimise antibodies prior to downstream assays and clinical delivery. Join Brittney Mills, PhD, as she explains how AbbVie uses
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