Dianthus | Affinity Screening
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2:30WatchDianthus: Tackle your most challenging affinity screenings with breakthrough Spectral Shift technology
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22:23WatchSelective degradation of cancer target WDR5 — Evaluation of PROTACs binary and ternary affinities with Spectral Shift
Chances are your company’s research and development pipeline includes several PROTAC candidates — placing you with many others in the race to bring successful and efficient protein degraders to the cl
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16:42WatchHow to keep your degrader pipeline moving forward with Dianthus
The development of your protein degrader is a multi-step and complex process usually packed with challenges that if left unsolved will delay the progress of your project. What if you could overcome co
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37:25WatchPut your challenging affinity screening campaigns back on track — after you’ve tried everything else
When you’re entrusted with developing therapeutics for challenging or undruggable targets, it’s a struggle to characterize molecular interactions. And it’s not for lack of effort or expertise — SPR an
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Top 8 targeted protein degradation conferences of 2023 at a glance
Use this downloadable list of 2023 Targeted Protein Degradation conferences to choose which one(s) to attend. Learn when and where they’ll happen, who’ll be there, and the main focus.
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Characterize your PROTAC hook effect with flexible and in-solution affinity measurements for results you can trust
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ReadNanoTemper Technologies launches Spectral Shift, a breakthrough technology that changes the game for affinity-based screenings
NanoTemper Technologies, announced today the launch of Spectral Shift technology within their Dianthus instrument, built to handle the most challenging affinity-based screenings in drug discovery....
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Ready to tackle your challenging affinity screening?
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Rely on Dianthus to overcome roadblocks in your PROTAC characterizations
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Finally tackle your most challenging affinity screenings with breakthrough Spectral Shift technology with Dianthus
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Read10 terms to help you more easily understand targeted protein degradation
Targeted Protein Degradation (TPD), a relatively new therapeutic approach, is making waves by targeting otherwise ‘undruggable’ proteins. PROTACs are the best-understood protein degraders, with...
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Going small to win big: Fragment-based screening in drug discovery
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Read9 Targeted Protein Degradation conferences you don’t want to miss in 2022
Update: See which 2023 conferences you should watch for With so much interest and investment in target protein degradation, a lot can happen in a year. Here are 9 conferences to get up-to-date on...
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ReadTargeted protein degradation promises to lead the way to effective drugs for challenging targets
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ReadHigh-throughput determination of protein affinities using unmodified peptide libraries in nanomolar scale
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ReadWhy so many companies are betting on PROTACs as a superior therapeutic modality
With PROTACs currently in the clinical and preclinical stages, they are making exciting progress towards successfully treating patients who have been waiting for effective therapies for certain...
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35:47WatchImprove your protein degrader design with new ways to discover E3 ligase ligands
Targeted protein degradation using molecular glues or proteolysis-targeting chimeras (PROTACs) is an increasingly important therapeutic modality, especially for undruggable targets. Even with candidat
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ReadMST and TRIC technology to reliably study PROTAC binary and ternary binding in drug development
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ReadFast Mek1 hit identification with TRIC technology correlates well with other biophysical methods
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56:52WatchAdventures in drug discovery - The quest for your best small molecule
Are you working in the field of small molecule drug discovery? Join this webinar to explore the drug discovery workflow and discover tools that can help in your quest for the most promising lead com
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59:35WatchHow to improve the function of your PROTAC degrader by understanding ternary complex formation
Bifunctional degrader molecules (aka PROTACs) and molecular glues recruit proteins to E3 ubiquitin ligases, forming a ternary complex that enables ubiquitination and degradation of the target
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