Dianthus | Affinity Screening

  • Characterize your PROTAC hook effect with flexible and in-solution affinity measurements for results you can trust

    Characterize your PROTAC hook effect with flexible and in-solution affinity measurements for results you can trust

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  • Rely on Dianthus to overcome roadblocks in your PROTAC characterizations

    Rely on Dianthus to overcome roadblocks in your PROTAC characterizations

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  • Put your challenging affinity screening campaigns back on track — after you’ve tried everything else37:25

    Put your challenging affinity screening campaigns back on track — after you’ve tried everything else

    When you’re entrusted with developing therapeutics for challenging or undruggable targets, it’s a struggle to characterize molecular interactions. And it’s not for lack of effort or expertise — SPR an

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  • NanoTemper Technologies launches Spectral Shift, a breakthrough technology that changes the game for affinity-based screenings

    NanoTemper Technologies launches Spectral Shift, a breakthrough technology that changes the game for affinity-based screenings

    NanoTemper Technologies, announced today the launch of Spectral Shift technology within their Dianthus instrument, built to handle the most challenging affinity-based screenings in drug discovery....

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  • Finally tackle your most challenging affinity screenings with breakthrough Spectral Shift technology with Dianthus

    Finally tackle your most challenging affinity screenings with breakthrough Spectral Shift technology with Dianthus

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  • Dianthus: Tackle your most challenging affinity screenings with breakthrough Spectral Shift technology2:30

    Dianthus: Tackle your most challenging affinity screenings with breakthrough Spectral Shift technology

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  • Going small to win big: Fragment-based screening in drug discovery

    Going small to win big: Fragment-based screening in drug discovery

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  • Ready to tackle your challenging affinity screening?

    Discover tools you can use

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  • How to find promising small molecule lead compounds with biophysical tools25:01

    How to find promising small molecule lead compounds with biophysical tools

    Watch this webinar if you’re working in the field of small molecule drug discovery and want to learn how scientists in this field use biophysical tools to search for the most promising lead compounds.

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  • 9 Targeted Protein Degradation conferences you don’t want to miss in 2022

    9 Targeted Protein Degradation conferences you don’t want to miss in 2022

    With so much interest and investment in target protein degradation, a lot can happen in a year. Here are 9 conferences to get up-to-date on recent progress and the latest approaches. You’ll not...

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  • 10 terms to help you more easily understand targeted protein degradation

    10 terms to help you more easily understand targeted protein degradation

    Targeted Protein Degradation (TPD), a relatively new therapeutic approach, is making waves by targeting otherwise ‘undruggable’ proteins. PROTACs are the best-understood protein degraders, with...

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  • Targeted protein degradation promises to lead the way to effective drugs for challenging targets

    Targeted protein degradation promises to lead the way to effective drugs for challenging targets

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  • High-throughput determination of protein affinities using unmodified peptide libraries in nanomolar scale

    High-throughput determination of protein affinities using unmodified peptide libraries in nanomolar scale

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  • Why so many companies are betting on PROTACs as a superior therapeutic modality

    Why so many companies are betting on PROTACs as a superior therapeutic modality

    With PROTACs currently in the clinical and preclinical stages, they are making exciting progress towards successfully treating patients who have been waiting for effective therapies for certain...

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  • Improve your protein degrader design with new ways to discover E3 ligase ligands35:47

    Improve your protein degrader design with new ways to discover E3 ligase ligands

    Targeted protein degradation using molecular glues or proteolysis-targeting chimeras (PROTACs) is an increasingly important therapeutic modality, especially for undruggable targets. Even with candidat

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  • MST and TRIC technology to reliably study PROTAC binary and ternary binding in drug development

    MST and TRIC technology to reliably study PROTAC binary and ternary binding in drug development

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  • Fast Mek1 hit identification with TRIC technology correlates well with other biophysical methods

    Fast Mek1 hit identification with TRIC technology correlates well with other biophysical methods

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  • Adventures in drug discovery - The quest for your best small molecule56:52

    Adventures in drug discovery - The quest for your best small molecule

    Are you working in the field of small molecule drug discovery? Join this webinar to explore the drug discovery workflow and discover tools that can help in your quest for the most promising lead com

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  • How to improve the function of your PROTAC degrader by understanding ternary complex formation59:35

    How to improve the function of your PROTAC degrader by understanding ternary complex formation

    Bifunctional degrader molecules (aka PROTACs) and molecular glues recruit proteins to E3 ubiquitin ligases, forming a ternary complex that enables ubiquitination and degradation of the target

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  • Tackle undruggable targets by screening for binary and ternary PROTAC interactions using Dianthus

    Tackle undruggable targets by screening for binary and ternary PROTAC interactions using Dianthus

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  • How to build an effective protein degrader

    How to build an effective protein degrader

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