Direct comparison of binding affinities from Spectral Shift and SPR for biotinylated targets

As challenging targets continue to enter your company’s portfolio, the need to diversify your biophysical toolbox to screen for hits and validate leads is clearer than ever. There’s now a way for easy and direct orthogonal validation of your SPR leads using your existing biotinylated targets. Additionally, this approach can become your go-to method when it becomes difficult to get results from SPR.

This infographic highlights how easy it is to validate your SPR hits using Spectral Shift technology and the Biotinylated Target Labeling kit. 

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Screening for p38 ligands: From assay optimization to lead validation in 2 days
Screening for p38 ligands: From assay optimization to lead validation in 2 days

Dianthus is a biophysical screening instrument that uses Spectral Shift technology to measure molecular int...

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Applying Spectral Shift technology to study IDPs: Direct binding and displacement assays of MYC:MAX inhibitors
Applying Spectral Shift technology to study IDPs: Direct binding and displacement assays of MYC:MAX inhibitors

MYC is an important therapeutic target that associates with MAX to regulate gene transcription. Its lack of...

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