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How Merck KGaA uses light scattering measurements for better developability assessment of biologic therapeutics
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Biologics developability: learn how Merck uses Prometheus Panta to create developability profiles for their mAbs
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MST untangles the intricacy of a multimeric protein complex in its native form
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Quantifying oligonucleotides binding to human serum albumin with MST: A faster and precise approach for drug candidates ADME profiling
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Fast molecular interaction screening of epigenetic gene regulator G9a with fragments from a large chemical space
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Rapid Quantification of Unfolded Proteins for Quality Control and Optimization of Storage Conditions
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Fast and accurate evaluation of oxidation-induced destabilization of mAbs
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Protein labeling – improved quantitation of biomolecular interactions by MST using the RED-NHS 2nd generation labeling kit
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Purification-free labeling in whole cell lysate and binding characterization by MST
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Determination of low-picomolar affinities of sgRNAs and crRNA/tracrRNAs for Cas9
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One-step, purification-free and site-specific labeling of polyhistidine-tagged proteins for MST
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Interaction of maltose binding protein (MBP) with maltose in a truly label-free assay
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Studying the interaction of the antibody-drug conjugate SYD985 with an anti-toxin antibody
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Anaerobic MicroScale Thermophoresis reveals the redox dependency of ferredoxin in mitochondrial Fe/S biogenesis
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Studying the interaction of membrane enzyme PgIB with substrate and inhibitory peptide
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Analyzing the binding affinity of aptamer quantum dot conjugates to VEGF
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Thermodynamic characterization of DNA hybridization
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The decondensation factor 31 binds to mono-nucleosomes
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The decondensation factor 31 specifically binds to ssRNA but not to ssDNA or dsDNA
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The decondensation factor 31 specifically interacts with histones H3 and H4 but not H2A and H2B
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