Biologics

  • The biologics researcher's guide to DLS

    The biologics researcher's guide to DLS

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  • Use of self-interaction parameters derived from light scattering experiments for better developability assessment of biologic therapeutics

    Use of self-interaction parameters derived from light scattering experiments for better developability assessment of biologic therapeutics

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  • In pursuit of stability enhancement of a prostate cancer targeting antibody derived from a transgenic animal platform

    In pursuit of stability enhancement of a prostate cancer targeting antibody derived from a transgenic animal platform

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  • Looking for the optimal formulation for your biologics candidates?

    NanoTemper tools can help

    Find out how
  • High-throughput feasible screening tool for determining enzyme stabilities against organic solvents directly from crude extracts

    High-throughput feasible screening tool for determining enzyme stabilities against organic solvents directly from crude extracts

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  • DLS easily explained: What it tells you about your protein34:16

    DLS easily explained: What it tells you about your protein

    Join this webinar to learn about the physical phenomenon that drives Dynamic Light Scattering (DLS), and see a few examples of how DLS gives you deeper insights.

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  • Orthogonal methods for characterizing the unfolding of therapeutic monoclonal antibodies: differential scanning calorimetry, isothermal...

    Orthogonal methods for characterizing the unfolding of therapeutic monoclonal antibodies: differential scanning calorimetry, isothermal...

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  • What is Dynamic Light Scattering (and 4 reasons it’s useful for protein research)

    What is Dynamic Light Scattering (and 4 reasons it’s useful for protein research)

    Any researcher looking to better understand their protein’s behavior can benefit from the information provided by Dynamic Light Scattering (DLS). Here’s an overview of DLS and how it’s useful for...

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  • Stability optimization of engineered mAbs

    Stability optimization of engineered mAbs

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  • The autocorrelation function: the key to understanding your biological molecules25:16

    The autocorrelation function: the key to understanding your biological molecules

    Dynamic Light Scattering (DLS) is a technique that allows researchers to accurately size their biologic molecules and determine the distribution of particle sizes in a solution. In order to turn scatt

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  • Multi-parameter formulation development for an HIV-vaccine protein with direct validation of epitope binding18:48

    Multi-parameter formulation development for an HIV-vaccine protein with direct validation of epitope binding

    Join Thomas Schubert, CEO of 2bind, as he walks through experiments done on the Prometheus Panta to determine the optimal buffer for a vaccine candidate.

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  • Stability liabilities of biotherapeutic proteins: Early assessment as mitigation strategy

    Stability liabilities of biotherapeutic proteins: Early assessment as mitigation strategy

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  • The new gold standard in biologic characterization – Develop your biologics faster and better with Prometheus30:05

    The new gold standard in biologic characterization – Develop your biologics faster and better with Prometheus

    Development of therapeutic antibodies is a long and costly process. One key indicator of whether biologic candidates will be successful is stability. Prometheus enables rapid and precise characterizat

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  • Sizing accuracy and intra-assay precision of DLS measurements with Prometheus Panta

    Sizing accuracy and intra-assay precision of DLS measurements with Prometheus Panta

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  • Use of high-throughput methods for early stage formulation evaluation and their correlation to stability studies28:21

    Use of high-throughput methods for early stage formulation evaluation and their correlation to stability studies

    AbbVie preformulation is an early discovery biologics group working to optimise antibodies prior to downstream assays and clinical delivery. Join Brittney Mills, PhD, as she explains how AbbVie uses

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  • Peptide-MHC I complex stability measured by nanoscale differential scanning fluorimetry reveals molecular mechanism of thermal denaturation

    Peptide-MHC I complex stability measured by nanoscale differential scanning fluorimetry reveals molecular mechanism of thermal denaturation

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  • Rapid and precise biosimilar candidate profiling by nanoDSF

    Rapid and precise biosimilar candidate profiling by nanoDSF

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  • Measuring stability to more effectively select therapeutic antibody candidates23:44

    Measuring stability to more effectively select therapeutic antibody candidates

    This therapeutic antibody drug development webinar discusses the idea of limiting the substantial investment of time, money, or resources.

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  • Understanding unfolding and refolding of the antibody fragment (Fab). I. In-vitro study

    Understanding unfolding and refolding of the antibody fragment (Fab). I. In-vitro study

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  • Evaluation of slow equilibration kinetics in antibody chemical denaturation experiments

    Evaluation of slow equilibration kinetics in antibody chemical denaturation experiments

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  • An application of nano differential scanning fluorimetry for higher order structure assessment between mAb originator and biosimilars

    An application of nano differential scanning fluorimetry for higher order structure assessment between mAb originator and biosimilars

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