Biologics
![De-risk your antibody characterization workflows with high-quality, multi-parameter stability data from Prometheus Panta](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fres.cloudinary.com%2Fuf-553493%2Fimage%2Fupload%2Fv1716468987%2FUberflip_Thumbnail_ert2xy.png&size=1&version=1716469212&sig=df3c439708b93ebbd43ef4c1ecc3ce7e&default=hubs%2Ftilebg-videos.jpg)
De-risk your antibody characterization workflows with high-quality, multi-parameter stability data from Prometheus Panta
Get developability profiles for monoclonal antibodies with stability data from Prometheus Panta to inform on rational design and selection of therapeutic constructs that will succeed in the clinic.
![Biologics Formulation: Select optimal buffer conditions with multi-parameter stability characterization from Prometheus Panta](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fcontent.cdntwrk.com%2Ffiles%2FaHViPTg2NTQ5JmNtZD1pdGVtZWRpdG9yaW1hZ2UmZmlsZW5hbWU9aXRlbWVkaXRvcmltYWdlXzY2MmZkZmJjOTJmZjYucG5nJnZlcnNpb249MDAwMCZzaWc9OGYxOGQ0ODg5ZTVhYjJkNzVlYjI1MmU5MDI0OWNjOGY%25253D&size=1&version=1714413510&sig=e7113872c465e6d045c346261714b0f9&default=hubs%2Ftilebg-videos.jpg)
Biologics Formulation: Select optimal buffer conditions with multi-parameter stability characterization from Prometheus Panta
Learn how to identify optimal buffer conditions during pre-formulation, with multi-parameter stability characterization from Prometheus Panta, a tool to collect thermal and colloidal data while saving
![5 considerations for buffer optimization during biologics pre-formulation](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fnanotempertech.com%2Fwp-content%2Fuploads%2F2024%2F05%2FAdobeStock_599334474-scaled.jpeg&size=1&version=1720514632&sig=4efcbf35ba24076301419c63e6879d61&default=hubs%2Ftilebg-blogs.jpg)
5 considerations for buffer optimization during biologics pre-formulation
The work of pre-formulations scientists is critical to de-risk the entire development process for biologics. Read on to learn more about what to consider about your buffer components for...
![5 types of formulation excipients and how they impact biologics stability](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fnanotempertech.com%2Fwp-content%2Fuploads%2F2024%2F05%2FAdobe-stock-image-test-tubes-blog.png&size=1&version=1718397767&sig=89bdab4cc57b798cc127758303da3267&default=hubs%2Ftilebg-blogs.jpg)
5 types of formulation excipients and how they impact biologics stability
For pre-formulations researchers looking to find buffers that stabilize early development biologic products, buffer optimization goes beyond the pH and salt concentration of the solution....
![Assess the impact of bioconjugation with multi-parameter stability characterization](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fcontent.cdntwrk.com%2Ffiles%2FaHViPTg2NTQ5JmNtZD1pdGVtZWRpdG9yaW1hZ2UmZmlsZW5hbWU9aXRlbWVkaXRvcmltYWdlXzY1ZjliNDgxNmQ1NzQucG5nJnZlcnNpb249MDAwMCZzaWc9MWNhOTdkMDc3OWNkYjJmZjdiZjAwMjg5OWM3OGRjNjY%25253D&size=1&version=1714412448&sig=330d90a750b1cef76374a164ef6a281c&default=hubs%2Ftilebg-videos.jpg)
Assess the impact of bioconjugation with multi-parameter stability characterization
Characterize the developability of antibody-drug conjugates: Multi-parameter stability assessment with Prometheus Panta makes it possible to examine multiple aspects of ADC stability in parallel.
![Get predictive insight into your ADC’s stability with these 3 experiments](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fnanotempertech.com%2Fwp-content%2Fuploads%2F2024%2F03%2FAdobeStock_453943865-scaled.jpeg&size=1&version=1720526038&sig=786dfe08242a004607249257b2080e71&default=hubs%2Ftilebg-blogs.jpg)
Get predictive insight into your ADC’s stability with these 3 experiments
Learn how it’s possible to use the Prometheus Panta to extrapolate how your low concentration sample will behave once it’s scaled up and at higher concentrations used for clinical administration.
![How stability prediction experiments give you confidence in your ADCs](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fcontent.cdntwrk.com%2Ffiles%2FaHViPTg2NTQ5JmNtZD1pdGVtZWRpdG9yaW1hZ2UmZmlsZW5hbWU9aXRlbWVkaXRvcmltYWdlXzY1ZTZmZDYzNDU0MTgucG5nJnZlcnNpb249MDAwMCZzaWc9MGM1ZGRmN2ZmYzdjZmUyYTViODI3ZmE1OWQyYTM2MTY%25253D&size=1&version=1715958612&sig=3b6a68bd993d755ae01d447a96466cb2&default=hubs%2Ftilebg-videos.jpg)
How stability prediction experiments give you confidence in your ADCs
For antibody-drug conjugate (ADC) development, scientists rely on stability experiments using fluorescence and light scattering techniques to predict the conjugated molecule's behavior.
![What are ADCs and how do they work against cancer?](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fcontent.cdntwrk.com%2Ffiles%2FaHViPTg2NTQ5JmNtZD1pdGVtZWRpdG9yaW1hZ2UmZmlsZW5hbWU9aXRlbWVkaXRvcmltYWdlXzY1ZTg1NDI2ZTgwOWUucG5nJnZlcnNpb249MDAwMCZzaWc9MmU4NjBiNDIxYTk1YmMxNzI2NTBmYjZkYTU2YmI4YWM%25253D&size=1&version=1709724989&sig=9df082f24d96f920de28a7b9e85c2895&default=hubs%2Ftilebg-videos.jpg)
What are ADCs and how do they work against cancer?
In this short animated video, learn the basics of how antibody-drug conjugates (ADCs) are engineered and why that makes them such powerful tools to target cancers with precision.
Trying to select the best candidates for biologics development?
A combination of thermal and colloidal stability characterization will help
![De-risk your ADC development process with these stability considerations](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fnanotempertech.com%2Fwp-content%2Fuploads%2F2023%2F12%2FBlog-Cropping-Official.jpg&size=1&version=1709636440&sig=36e9db54191503c1e5578d9051e9b088&default=hubs%2Ftilebg-blogs.jpg)
De-risk your ADC development process with these stability considerations
Antibody-drug conjugates, or ADCs, are revolutionary therapeutics that represent a growing proportion of the biologics market. They combine the targeting power of a monoclonal antibody, which is...
Learn how to select and optimize your biologic candidates for better clinical outcomes
Read more![How to mitigate risk during ADC development with multi-parameter stability characterization](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fcontent.cdntwrk.com%2Ffiles%2FaHViPTg2NTQ5JmNtZD1pdGVtZWRpdG9yaW1hZ2UmZmlsZW5hbWU9aXRlbWVkaXRvcmltYWdlXzY1MzdjOGYzOWU1YmMucG5nJnZlcnNpb249MDAwMCZzaWc9ZDRlMjY4YzBhYTFkZDc2ZmY0MGUzMTYwMjZkNDE5ZmU%25253D&size=1&version=1709636476&sig=e160a5a2f2da8b58f82159f13e5020e5&default=hubs%2Ftilebg-videos.jpg)
How to mitigate risk during ADC development with multi-parameter stability characterization
To assess the developability properties of antibody-drug conjugates (ADCs) learn about multi-parameter characterization of thermal and colloidal stability with Prometheus Panta using nanoDSF and DLS
![5 biologics conferences you won’t want to miss in 2024](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fnanotempertech.com%2Fwp-content%2Fuploads%2F2024%2F02%2FAdobeStock_563771703-scaled-e1707373102293.jpeg&size=1&version=1709370030&sig=c5e701656b450d5b2fc9bf780062a5ef&default=hubs%2Ftilebg-blogs.jpg)
5 biologics conferences you won’t want to miss in 2024
Use this list of crowd-sourced favorites to kick-start your 2024 biologics conference plans. Find out when and where each conference takes place, who will be there, which topics are covered, and...
![Four integrated technologies for biologics developability assessment](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fcontent.cdntwrk.com%2Ffiles%2FaHViPTg2NTQ5JmNtZD1pdGVtZWRpdG9yaW1hZ2UmZmlsZW5hbWU9aXRlbWVkaXRvcmltYWdlXzYzOTg4NzgyNTAxNGMuanBlZyZ2ZXJzaW9uPTAwMDAmc2lnPWFiMTc1ZTJhZmRmZGY1ZTBjZTY4YzgyMjMxMDAwMGY5&size=1&version=1713519251&sig=b3f93dee9e36d2d9624e2a9ab20463b2&default=hubs%2Ftilebg-videos.jpg)
Four integrated technologies for biologics developability assessment
The decisions you make about your biologics candidates early in the pipeline ultimately affect their success as therapeutics. Combine sizing and stability information to develop successful biologics
![How four stability assessment technologies support biologics early development](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fcontent.cdntwrk.com%2Ffiles%2FaHViPTg2NTQ5JmNtZD1pdGVtZWRpdG9yaW1hZ2UmZmlsZW5hbWU9aXRlbWVkaXRvcmltYWdlXzY1NWI2YzJlMmIxN2QucG5nJnZlcnNpb249MDAwMCZzaWc9NTUwNjdiN2QyOTUwYmU3NzJhYjgwNGJlOTk0MjM3N2Q%25253D&size=1&version=1709636584&sig=35aa4edd7529f263ba8e276e8d51c1c4&default=hubs%2Ftilebg-blogs.jpg)
How four stability assessment technologies support biologics early development
During early development of biologics, there are many attributes scientists evaluate for developability. Measure them with biophysical characterization using nanoDSF, DLS, backreflection, and SLS.
![Conversation: How Aaron Frimel from Thermo Fisher Scientific approaches biologics formulation](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fcontent.cdntwrk.com%2Ffiles%2FaHViPTg2NTQ5JmNtZD1pdGVtZWRpdG9yaW1hZ2UmZmlsZW5hbWU9aXRlbWVkaXRvcmltYWdlXzY1Njg5NWUxNmE0MTUucG5nJnZlcnNpb249MDAwMCZzaWc9YmI5OTZkNmY1YWQ2M2U2Y2NmOWJlNGM2OTYzOGUyZGU%25253D&size=1&version=1701353040&sig=760f4216303ee3c862160680eae99ae2&default=hubs%2Ftilebg-videos.jpg)
Conversation: How Aaron Frimel from Thermo Fisher Scientific approaches biologics formulation
Join this conversation to gain insight into how the Analytical and Formulation Sciences team at Thermo Fisher Scientific approaches stability assessment of biologic, and how the Prometheus Panta helps
![nanoDSF for biologics: How to interpret thermal unfolding profiles for your different applications](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fcontent.cdntwrk.com%2Ffiles%2FaHViPTg2NTQ5JmNtZD1pdGVtZWRpdG9yaW1hZ2UmZmlsZW5hbWU9aXRlbWVkaXRvcmltYWdlXzY1MTU2Mjk4OGFkYTYucG5nJnZlcnNpb249MDAwMCZzaWc9YWMyMDUwYmEwNzA4ZmJjMTA2OTdjZGJhZGE0NDcxZTA%25253D&size=1&version=1715958626&sig=46a94f2734cb38e896b6c7d7ba057c8e&default=hubs%2Ftilebg-videos.jpg)
nanoDSF for biologics: How to interpret thermal unfolding profiles for your different applications
Thermal stability screening is a common approach used to study the developability of a wide range of protein-based therapeutics. Among the different technologies available to perform thermal stability
![Thermal stability measurements for biologics developability profiling](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fcontent.cdntwrk.com%2Ffiles%2FaHViPTg2NTQ5JmNtZD1pdGVtZWRpdG9yaW1hZ2UmZmlsZW5hbWU9aXRlbWVkaXRvcmltYWdlXzY1MDBiNzI5MDM5MjYucG5nJnZlcnNpb249MDAwMCZzaWc9ZWNlOTAzMWY4MGQ0OGI3MzM0NTQ3OTQwZTBkMDU2Mjg%25253D&size=1&version=1709636630&sig=d86c8fb5a16acca0f7210ecb0b30a3a1&default=hubs%2Ftilebg-videos.jpg)
Thermal stability measurements for biologics developability profiling
Learn about four methods for thermal stability measurements: DSC, CD, DSF and nanoDSF. You'll review their pros and cons, what they data tell you and why it's important for biologics developability.
![Why nanoDSF is the preferred method to assess the thermal stability of your therapeutic proteins](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fcontent.cdntwrk.com%2Ffiles%2FaHViPTg2NTQ5JmNtZD1pdGVtZWRpdG9yaW1hZ2UmZmlsZW5hbWU9aXRlbWVkaXRvcmltYWdlXzY1OWZmYWI4MTQ1NTIucG5nJnZlcnNpb249MDAwMCZzaWc9ZDRhNmY2NDYzNDExYWU4MTY3MThlOTMzM2YxYmYzY2Q%25253D&size=1&version=1704983235&sig=e79dd284a547082b5a4fc63c36a51fa2&default=hubs%2Ftilebg-blogs.jpg)
Why nanoDSF is the preferred method to assess the thermal stability of your therapeutic proteins
Learn about Differential Scanning Calorimetry (DSC), Circular Dichroism (CD), Extrinsic Differential Scanning Fluorimetry, and nano-Differential Scanning Fluorimetry for thermal stability of proteins
![The biologics researcher's mini-guide to screening candidates with nanoDSF](https://content.cdntwrk.com/files/aT0xNDk4ODUwJnA9MCZ2ZXJzaW9uPTEmY21kPXYmc2lnPTljZjdlNjFmYWRkZGI0N2QyMzU1OTIxYzgxYzM2ZjZk/-w-320.jpg)
The biologics researcher's mini-guide to screening candidates with nanoDSF
Read this nanoDSF guide to learn how nano-Differential Scanning Fluorimetry (nanoDSF) uses your protein’s intrinsic fluorescence to determine its melting temperature, Tm and onset of melting, Ton.
Trying to select the best candidates for biologics development?
A combination of thermal and colloidal stability characterization will help
Select the best biologics candidates with high-quality, multi-parameter stability characterization
Learn how to select and optimize your biologic candidates for better clinical outcomes
Read more![How stability characterization parameters help you create biologics developability profiles](https://content.cdntwrk.com/mediaproxy?url=https%3A%2F%2Fnanotempertech.com%2Fwp-content%2Fuploads%2F2023%2F07%2Fcreate-biologics-developability-profiles-Featured-Image.png&size=1&version=1720526038&sig=01973e7b047cf14e14a193c790eaae1c&default=hubs%2Ftilebg-blogs.jpg)
How stability characterization parameters help you create biologics developability profiles
Developability profiles help you avoid risk by collecting many quality attributes associated with each candidate, enabling you to rank each candidate by the most optimal attributes and make a...
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