Biologics
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Select the best biologics candidates with high-quality, multi-parameter stability characterization
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The biologics researcher's guide to DLS
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Journey of an mAb through IND and BLA filing
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Looking for the optimal formulation for your biologics candidates?
Find out how
NanoTemper tools can help -
1:41
Prometheus Panta: The new gold standard for biologics characterization
Choosing the right stability characterization tool for your biologics research is a big commitment. You’re going to be screening and optimizing lots of candidates, and you’ll need data on thermal stab
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Use of self-interaction parameters derived from light scattering experiments for better developability assessment of biologic therapeutics
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Your guide to efficiently develop antibody-based therapeutics
How to measure stability, why it's important, and where it belongs in the workflow
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In pursuit of stability enhancement of a prostate cancer targeting antibody derived from a transgenic animal platform
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High-throughput feasible screening tool for determining enzyme stabilities against organic solvents directly from crude extracts
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34:16
DLS easily explained: What it tells you about your protein
Join this webinar to learn about the physical phenomenon that drives Dynamic Light Scattering (DLS), and see a few examples of how DLS gives you deeper insights.
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Orthogonal methods for characterizing the unfolding of therapeutic monoclonal antibodies: differential scanning calorimetry, isothermal...
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What is Dynamic Light Scattering (and 4 reasons it’s useful for protein research)
Any researcher looking to better understand their protein’s behavior can benefit from the information provided by Dynamic Light Scattering (DLS). Here’s an overview of DLS and how it’s useful for...
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Stability optimization of engineered mAbs
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25:16
The autocorrelation function: the key to understanding your biological molecules
Dynamic Light Scattering (DLS) is a technique that allows researchers to accurately size their biologic molecules and determine the distribution of particle sizes in a solution. In order to turn scatt
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18:48
Multi-parameter formulation development for an HIV-vaccine protein with direct validation of epitope binding
Join Thomas Schubert, CEO of 2bind, as he walks through experiments done on the Prometheus Panta to determine the optimal buffer for a vaccine candidate.
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Stability liabilities of biotherapeutic proteins: Early assessment as mitigation strategy
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30:05
The new gold standard in biologic characterization – Develop your biologics faster and better with Prometheus
Development of therapeutic antibodies is a long and costly process. One key indicator of whether biologic candidates will be successful is stability. Prometheus enables rapid and precise characterizat
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Sizing accuracy and intra-assay precision of DLS measurements with Prometheus Panta
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28:21
Use of high-throughput methods for early stage formulation evaluation and their correlation to stability studies
AbbVie preformulation is an early discovery biologics group working to optimise antibodies prior to downstream assays and clinical delivery. Join Brittney Mills, PhD, as she explains how AbbVie uses
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Peptide-MHC I complex stability measured by nanoscale differential scanning fluorimetry reveals molecular mechanism of thermal denaturation
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Rapid and precise biosimilar candidate profiling by nanoDSF
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