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  • Fragment Screening: Save time and sample with Spectral Shift technology18:36

    Fragment Screening: Save time and sample with Spectral Shift technology

    Many methods used in fragment-based drug discovery pose real challenges — SPR often struggles to detect true hits due to fragments’ small mass, DSF can have high rates of false positives, and NMR equi

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  • De-risk your antibody characterization workflows with high-quality, multi-parameter stability data from Prometheus Panta16:24

    De-risk your antibody characterization workflows with high-quality, multi-parameter stability data from Prometheus Panta

    Get developability profiles for monoclonal antibodies with stability data from Prometheus Panta to inform on rational design and selection of therapeutic constructs that will succeed in the clinic.

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  • NanoTemper brings Spectral Shift technology to the protein production market with Andromeda X, enabling biopharma and CROs

    NanoTemper brings Spectral Shift technology to the protein production market with Andromeda X, enabling biopharma and CROs

    NanoTemper Technologies, well known for creating biophysical tools that accelerate the work of drug discovery researchers, brings their groundbreaking Spectral Shift technology to the protein...

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  • 5 considerations for buffer optimization during biologics pre-formulation

    5 considerations for buffer optimization during biologics pre-formulation

    Formulation development is a long, ongoing process during a candidate’s lifecycle. Broadly, it’s segmented into three categories: pre-formulation, formulation, and process development. The work of...

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  • 5 types of formulation excipients and how they impact biologics stability

    5 types of formulation excipients and how they impact biologics stability

    For pre-formulations researchers looking to find buffers that stabilize early development biologic products, buffer optimization goes beyond the pH and salt concentration of the solution....

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  • Biologics Formulation: Select optimal buffer conditions with multi-parameter stability characterization from Prometheus Panta22:59

    Biologics Formulation: Select optimal buffer conditions with multi-parameter stability characterization from Prometheus Panta

    Learn how to identify optimal buffer conditions during pre-formulation, with multi-parameter stability characterization from Prometheus Panta, a tool to collect thermal and colloidal data while saving

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  • Measure the strength of any interaction with versatile labeling options for Spectral Shift

    Measure the strength of any interaction with versatile labeling options for Spectral Shift

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  • How biologics teams use Dynamic Light Scattering to identify leading candidates13:12

    How biologics teams use Dynamic Light Scattering to identify leading candidates

    Watch this 15 min video to learn how groups in early biologics development and formulation use Dynamic Light Scattering (DLS) to make informed decisions that de-risk downstream biologics development.

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  • Virtual Monolith X Demo: Free-in-solution affinity measurements with minimal sample consumption​15:19

    Virtual Monolith X Demo: Free-in-solution affinity measurements with minimal sample consumption​

    The tool you choose to measure affinities should tackle a diverse range of targets and ligands that come your way — such as GPCRs, IDPs, or cancer-related proteins. And, you should get data that help

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  • Three things we took away from attending Drug Discovery Chemistry in 2024

    Three things we took away from attending Drug Discovery Chemistry in 2024

    Drug Discovery Chemistry is an annual event that focuses solely on early drug discovery, where scientists from around the world gather to showcase their research and participate in thoughtful...

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  • Virtual Prometheus Panta demo: Four integrated technologies for protein stability characterization9:42

    Virtual Prometheus Panta demo: Four integrated technologies for protein stability characterization

    Your protein stability characterization projects require tools that provide high-precision, high-quality data to support your selection process. Watch this 10 min walkthrough of Prometheus Panta.

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  • Get predictive insight into your ADC’s stability with these 3 experiments

    Get predictive insight into your ADC’s stability with these 3 experiments

    When developing ADCs, there are some strategies for protein assessment that will help mitigate the risk of destabilizing the final product during early development, particularly when optimizing...

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  • Assess the impact of bioconjugation with multi-parameter stability characterization17:08

    Assess the impact of bioconjugation with multi-parameter stability characterization

    Characterize the developability of antibody-drug conjugates: Multi-parameter stability assessment with Prometheus Panta makes it possible to examine multiple aspects of ADC stability in parallel.

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  • What are ADCs and how do they work against cancer?0:40

    What are ADCs and how do they work against cancer?

    In this short animated video, learn the basics of how antibody-drug conjugates (ADCs) are engineered and why that makes them such powerful tools to target cancers with precision.

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  • How stability prediction experiments give you confidence in your ADCs19:07

    How stability prediction experiments give you confidence in your ADCs

    For antibody-drug conjugate (ADC) development, scientists rely on stability experiments using fluorescence and light scattering techniques to predict the conjugated molecule's behavior.

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  • The power of Monolith X for Characterizing GPCRs: Accelerating Binding Affinity Measurements20:31

    The power of Monolith X for Characterizing GPCRs: Accelerating Binding Affinity Measurements

    To understand signaling pathways, Spectral Shift technology allows for accurate bindings affinity measurements of membrane proteins like GPCRs in close to native conditions.

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  • 5 biologics conferences you won’t want to miss in 2024

    5 biologics conferences you won’t want to miss in 2024

    Use this list of crowd-sourced favorites to kick-start your 2024 biologics conference plans. Find out when and where each conference takes place, who will be there, which topics are covered, and...

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  • Attend these targeted protein degradation conferences in 2024 to stay in the know

    Attend these targeted protein degradation conferences in 2024 to stay in the know

    Attending dedicated targeted protein degradation conferences and tracks is a great way to keep up with this rapidly evolving field. Here are 8 conferences you’ll want to attend in 2024.

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  • Applying Spectral Shift technology to study IDPs: Direct binding and displacement assays of MYC:MAX inhibitors11:48

    Applying Spectral Shift technology to study IDPs: Direct binding and displacement assays of MYC:MAX inhibitors

    MYC is an important therapeutic target that associates with MAX to regulate gene transcription. Its lack of binding pockets and the presence of disordered regions make it a difficult protein to study

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  • Screening for p38 ligands: From assay optimization to lead validation in 2 days12:54

    Screening for p38 ligands: From assay optimization to lead validation in 2 days

    Dianthus is a biophysical screening instrument that uses Spectral Shift technology to measure molecular interactions for hit ID, hit-to-lead, and lead optimization. It offers a 384-well plate format a

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