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  • Automate your screening workflow for characterizing protein stability2:10

    Automate your screening workflow for characterizing protein stability

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  • Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways

    Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways

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  • Identification of pyroptosis inhibitors that target a reactive cysteine in gasdermin D

    Identification of pyroptosis inhibitors that target a reactive cysteine in gasdermin D

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  • The voltage-dependent anion channel 1 mediates amyloid ß toxicity and represents a potential target for AD therapy

    The voltage-dependent anion channel 1 mediates amyloid ß toxicity and represents a potential target for AD therapy

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  • Solution-based determination of dissociation constants for the binding of Aß42 to antibodies

    Solution-based determination of dissociation constants for the binding of Aß42 to antibodies

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  • A biophysical approach to the identification of novel ApoE chemical probes

    A biophysical approach to the identification of novel ApoE chemical probes

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  • An engineered monomer binding-protein for alpha-syn efficiently inhibits the proliferation of amyloid fibrils

    An engineered monomer binding-protein for alpha-syn efficiently inhibits the proliferation of amyloid fibrils

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  • Structural basis of small molecule targetability of monomeric tau protein

    Structural basis of small molecule targetability of monomeric tau protein

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  • Improve therapeutic monoclonal antibody selection by knowing protein stability using Prometheus16:37

    Improve therapeutic monoclonal antibody selection by knowing protein stability using Prometheus

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  • Easily characterize the molecular mechanisms of neurodegenerative diseases

    Easily characterize the molecular mechanisms of neurodegenerative diseases

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  • Optimize antibody developability using Prometheus, the new gold standard for characterizing antibody stability

    Optimize antibody developability using Prometheus, the new gold standard for characterizing antibody stability

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  • New insights in plant science

    New insights in plant science

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  • Fast-track your hit screening assay development with the Buffer Exploration Kit

    Fast-track your hit screening assay development with the Buffer Exploration Kit

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  • A small compound targeting prohibitin with potential interest for cognitive deficit rescue in aging mice and tau pathology treatment

    A small compound targeting prohibitin with potential interest for cognitive deficit rescue in aging mice and tau pathology treatment

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  • Nano differential scanning fluorimetry for comparability studies of therapeutic proteins

    Nano differential scanning fluorimetry for comparability studies of therapeutic proteins

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  • Rescue of cognitive deficits in APP/PS1 mice by accelerating the aggregation of ß-amyloid peptide

    Rescue of cognitive deficits in APP/PS1 mice by accelerating the aggregation of ß-amyloid peptide

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  • The ACT domain in chloroplast precursor–phosphorylating STY kinases binds metabolites and allosterically regulates kinase activity

    The ACT domain in chloroplast precursor–phosphorylating STY kinases binds metabolites and allosterically regulates kinase activity

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  • Accelerating Protein Purification by Using Thermal Unfolding as a Guiding Tool45:48

    Accelerating Protein Purification by Using Thermal Unfolding as a Guiding Tool

    Cellular expression and purification of proteins are among the most widely used techniques in biology. Expressing proteins in stable, properly-folded states is a challenge that may be abated by monito

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  • Easily characterize binding interactions, measure stability, and evaluate the quality of your plant proteins

    Easily characterize binding interactions, measure stability, and evaluate the quality of your plant proteins

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  • Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles

    Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles

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  • Improving Large Molecule Production Processes by Integrating Innovative Technology Solutions50:24

    Improving Large Molecule Production Processes by Integrating Innovative Technology Solutions

    Process development for Fill & Finish activities of large molecule parenterals requires an orchestrated effort of multiple functions to deal with product specific critical quality attributes (CQAs) an

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