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Analyze self-interaction to predict viscosity and aggregation propensity at higher concentrations
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ReadFor protein degraders to tackle neurodegenerative diseases, these are the barriers they need to overcome
Neurodegenerative diseases (ND) and cancer are the two major targets in the pipelines of companies focused on targeted protein degradation as a therapeutic modality. Proteins involved in NDs —...
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32:05WatchTour Andromeda: how to screen for optimal expression of folded membrane proteins in crude lysate
Poor expression levels, solubilization, and stability — these are the daily challenges that your membrane protein production team faces every day. You go through long cycles of expression optimization
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25:16WatchThe autocorrelation function: the key to understanding your biological molecules
Dynamic Light Scattering (DLS) is a technique that allows researchers to accurately size their biologic molecules and determine the distribution of particle sizes in a solution. In order to turn scatt
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25:01WatchHow to find promising small molecule lead compounds with biophysical tools
Watch this webinar if you’re working in the field of small molecule drug discovery and want to learn how scientists in this field use biophysical tools to search for the most promising lead compounds.
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ReadWhy so many companies are betting on PROTACs as a superior therapeutic modality
With PROTACs currently in the clinical and preclinical stages, they are making exciting progress towards successfully treating patients who have been waiting for effective therapies for certain...
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ReadMST and TRIC technology to reliably study PROTAC binary and ternary binding in drug development
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28:21WatchUse of high-throughput methods for early stage formulation evaluation and their correlation to stability studies
AbbVie preformulation is an early discovery biologics group working to optimise antibodies prior to downstream assays and clinical delivery. Join Brittney Mills, PhD, as she explains how AbbVie uses
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14:01WatchHow to study molecular interactions of membrane proteins without compromising their native structure
The desire to use technology that allows you to study membrane proteins in close-to-native conditions is specifically important when it comes to interaction measurements. It’s always a question how mu
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12:06WatchHow to find expression and purification conditions that result in high levels of thermally stable membrane proteins
What you’ll learn It’s very common to experience low expression levels when producing membrane proteins — plus they’re finicky and unstable when they're outside of their native environment. Just know
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Read5 formulation changes you can evaluate with Dynamic Light Scattering to increase your biologics candidates’ success
Biologics researchers are deeply concerned with formulation. Formulation typically refers to the final development of a deliverable, biologically derived molecule (such as a protein, peptide,...
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The biologics researcher's guide to DLS
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ReadNanoTemper gets Top 100 award as one of Germany’s most innovative SMEs in 2021
NanoTemper has been given this year’s TOP 100 seal, an award that honors innovative German small and medium-sized companies. The TOP 100 innovation competition is organized by compamedia, and...
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ReadFast Mek1 hit identification with TRIC technology correlates well with other biophysical methods
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56:52WatchAdventures in drug discovery - The quest for your best small molecule
Are you working in the field of small molecule drug discovery? Join this webinar to explore the drug discovery workflow and discover tools that can help in your quest for the most promising lead com
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ReadNanoTemper’s Monolith wins top global design award: Red Dot Award
NanoTemper’s newest Monolith instrument has been awarded the Red Dot Award, an internationally recognized seal of excellence in design. Both bold aesthetics and user-friendly design have always...
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35:47WatchImprove your protein degrader design with new ways to discover E3 ligase ligands
Targeted protein degradation using molecular glues or proteolysis-targeting chimeras (PROTACs) is an increasingly important therapeutic modality, especially for undruggable targets. Even with candidat
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35:24WatchEffect of different SARS-CoV-2 variants on COVID 19 assays and vaccines
SARS-CoV-2, the causative agent of COVID-19, has an ssRNA genome of almost 30kb that encodes for a total of 26 proteins. Among the four structural viral protein, in particular the S protein stands out
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ReadNanoTemper launches Andromeda, helping Biopharma and CROs to increase efficiency of expression screening for membrane proteins
SOUTH SAN FRANCISCO, Calif. June 24, 2021 — NanoTemper Technologies, well-known for creating biophysical tools that tackle challenging characterizations, enters the protein production market with...
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Quickly screen for optimal expression levels and thermal stability for your toughest membrane proteins
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