Membrane Proteins
-
4:09
Did you say, “membrane proteins”? Challenge accepted!
Working with difficult targets like GPCRs and other membrane proteins? Because they live in the cell membrane, are hydrophobic and insoluble, have low expression levels, and require particular deter
-
nanoDSF: Label-free thermal unfolding assay of G Protein-coupled receptors for compound screening and buffer composition optimization
-
Lipids activate SecA for high affinity binding to the SecYEG complex
-
Working with tricky membrane proteins?
Find out how
NanoTemper tools can help -
Thermophoretic analysis of ligand-specific conformational states of the inhibitory glycine receptor embedded in copolymer nanodiscs
-
Detergent-free extraction of a functional low-expressing GPCR from a human cell line
-
Saposin lipid nanoparticles: A highly versatile and modular tool for membrane protein research
-
Phospholipid membrane fluidity alters ligand binding activity of a G protein-coupled receptor by shifting the conformational equilibrium
-
Phosphorylation of human aquaporin 2 (AQP2) allosterically controls its interaction with the lysosomal trafficking protein LIP5
-
Interactions of liposome embedded SNARE proteins
-
Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions
-
Molecular basis of nitrate uptake by the plant nitrate transporter NRT1.1
-
Structure of DtpA from E. coli in complex with Valganciclovir provides insights into drug binding of human PepT1
-
Structural basis of species-selective antagonist binding to the succinate receptor
-
Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals
-
Studying the interaction of membrane enzyme PgIB with substrate and inhibitory peptide
-
Lipid-like peptides can stabilize integral membrane proteins for biophysical and structural studies
-
Structural basis for substrate specificity and regulation of nucleotide sugar transporters in the lipid bilayer
-
Membrane (and soluble) protein stability and binding measurements in the lipid cubic phase using label-free DSF
-
nanoDSF thermal unfolding analysis of a membrane-bound esterase in various detergents
-
High-throughput stability screening for detergent-solubilized membrane proteins
-
Loading more...