Did you say, “membrane proteins”? Challenge accepted!

Working with difficult targets like GPCRs and other membrane proteins?

Because they live in the cell membrane, are hydrophobic and insoluble, have low expression levels, and require particular detergents to remove them from the cell membrane, it’s difficult to get a decent amount of folded and functional protein.

Listen in on the conversation between one of NanoTemper’s membrane protein experts, Claire, and her colleague, Paren, as they talk about how NanoTemper helps make working with membrane proteins easier.

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nanoDSF: Label-free thermal unfolding assay of G Protein-coupled receptors for compound screening and buffer composition optimization
nanoDSF: Label-free thermal unfolding assay of G Protein-coupled receptors for compound screening and buffer composition optimization

Working with tricky membrane proteins?

NanoTemper tools can help

Find out how