Monolith | Binding Affinity

5:33

Ready to characterize your most challenging interactions?

Discover tools to measure binding affinity

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NanoTemper’s Monolith wins top global design award: Red Dot Award

NanoTemper’s newest Monolith instrument has been awarded the Red Dot Award, an internationally recognized seal of excellence in design. Both bold aesthetics and user-friendly design have always...

Read

14:01

How to study molecular interactions of membrane proteins without compromising their native structure

The desire to use technology that allows you to study membrane proteins in close-to-native conditions is specifically important when it comes to interaction measurements. It’s always a question how mu

Watch

35:47

Improve your protein degrader design with new ways to discover E3 ligase ligands

Targeted protein degradation using molecular glues or proteolysis-targeting chimeras (PROTACs) is an increasingly important therapeutic modality, especially for undruggable targets. Even with candidat

Watch

Why so many companies are betting on PROTACs as a superior therapeutic modality

With PROTACs currently in the clinical and preclinical stages, they are making exciting progress towards successfully treating patients who have been waiting for effective therapies for certain...

Read

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35:24

Effect of different SARS-CoV-2 variants on COVID 19 assays and vaccines

SARS-CoV-2, the causative agent of COVID-19, has an ssRNA genome of almost 30kb that encodes for a total of 26 proteins. Among the four structural viral protein, in particular the S protein stands out

Watch

MST and TRIC technology to reliably study PROTAC binary and ternary binding in drug development

Read

27:20

Molecular interactions - a simple framework: Energy, energy, energy

Explore the complexities and drivers of molecular interactions with Dr. Tom Laue from the University of New Hampshire. He presented as a keynote speaker in the Protein Stability & Function: Can't have

Watch

33:11

Maximize stability & function of SARS-CoV-spike protein and ACE2 receptor using Monolith & Prometheus

Dr. Leah Pandiscia and Dr. Daniel Turman review how to integrate the Prometheus Panta and Monolith instruments in a characterization workflow demonstration, showing how to maximize stability and funct

Watch

NanoTemper’s Monolith wins top global design award: iF DESIGN AWARD 2021

NanoTemper’s newest Monolith instrument has been awarded the globally renowned iF DESIGN AWARD 2021. User-friendly design has always been a core focus in NanoTemper’s product development....

Read

25:40

Mischievous membrane proteins (and how to tame them)

Are you struggling to tame your mischievous membrane proteins? Find out how NanoTemper can help you to characterize even the most challenging membrane protein samples. You will learn how Prometheus ca

Watch

Targeted protein degradation promises to lead the way to effective drugs for challenging targets

Read

Are you building an effective protein degrader?

Read

Optimize the structure of your next round of PROTAC compounds by analyzing ternary binding affinities using Monolith

Read

Quantifying the interaction of phosphite with ABC transporters: MicroScale Thermophoresis and a novel his-tag labeling approach

Read

4 ways to help you overcome the limitations of current methods in neurodegenerative disease research

Read

Are you building an effective protein degrader? 4 questions to ask yourself to find out

Protein degraders are getting a lot of attention for being a new and promising modality to treat diseases such as cancer or Alzheimer’s disease. Rather than inhibiting the function of a protein,...

Read

Ddi1 is a ubiquitin-dependent protease

Read

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Monolith | Binding Affinity

See the new Monolith — characterize your most challenging interactions

Because you need to characterize the most challenging interactions

The researcher’s guide to measuring binding affinity and why it matters

NanoTemper’s Monolith wins top global design award: Red Dot Award

NanoTemper’s newest Monolith instrument has been awarded the Red Dot Award, an internationally recognized seal of excellence in design. Both bold aesthetics and user-friendly design have always...

How to study molecular interactions of membrane proteins without compromising their native structure

The desire to use technology that allows you to study membrane proteins in close-to-native conditions is specifically important when it comes to interaction measurements. It’s always a question how mu

Improve your protein degrader design with new ways to discover E3 ligase ligands

Targeted protein degradation using molecular glues or proteolysis-targeting chimeras (PROTACs) is an increasingly important therapeutic modality, especially for undruggable targets. Even with candidat

Why so many companies are betting on PROTACs as a superior therapeutic modality

With PROTACs currently in the clinical and preclinical stages, they are making exciting progress towards successfully treating patients who have been waiting for effective therapies for certain...

Effect of different SARS-CoV-2 variants on COVID 19 assays and vaccines

SARS-CoV-2, the causative agent of COVID-19, has an ssRNA genome of almost 30kb that encodes for a total of 26 proteins. Among the four structural viral protein, in particular the S protein stands out

MST and TRIC technology to reliably study PROTAC binary and ternary binding in drug development

Molecular interactions - a simple framework: Energy, energy, energy

Explore the complexities and drivers of molecular interactions with Dr. Tom Laue from the University of New Hampshire. He presented as a keynote speaker in the Protein Stability & Function: Can't have

Maximize stability & function of SARS-CoV-spike protein and ACE2 receptor using Monolith & Prometheus

Dr. Leah Pandiscia and Dr. Daniel Turman review how to integrate the Prometheus Panta and Monolith instruments in a characterization workflow demonstration, showing how to maximize stability and funct

NanoTemper’s Monolith wins top global design award: iF DESIGN AWARD 2021

NanoTemper’s newest Monolith instrument has been awarded the globally renowned iF DESIGN AWARD 2021. User-friendly design has always been a core focus in NanoTemper’s product development....

Mischievous membrane proteins (and how to tame them)

Are you struggling to tame your mischievous membrane proteins? Find out how NanoTemper can help you to characterize even the most challenging membrane protein samples. You will learn how Prometheus ca

Targeted protein degradation promises to lead the way to effective drugs for challenging targets

Are you building an effective protein degrader?

Optimize the structure of your next round of PROTAC compounds by analyzing ternary binding affinities using Monolith

Quantifying the interaction of phosphite with ABC transporters: MicroScale Thermophoresis and a novel his-tag labeling approach

4 ways to help you overcome the limitations of current methods in neurodegenerative disease research

Are you building an effective protein degrader? 4 questions to ask yourself to find out

Protein degraders are getting a lot of attention for being a new and promising modality to treat diseases such as cancer or Alzheimer’s disease. Rather than inhibiting the function of a protein,...

Ddi1 is a ubiquitin-dependent protease