Monolith | Binding Affinity

  • See the new Monolith — characterize your most challenging interactions5:33

    See the new Monolith — characterize your most challenging interactions

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  • Because you need to characterize the most challenging interactions

    Because you need to characterize the most challenging interactions

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  • NanoTemper Technologies debuts the newly redesigned Monolith, offering higher-quality molecular interaction measurements for very challengin

    NanoTemper Technologies debuts the newly redesigned Monolith, offering higher-quality molecular interaction measurements for very challengin

    PRESS RELEASE South San Francisco, CA. NanoTemper Technologies, well-known for creating biophysical tools that address challenging characterizations, today announced the new Monolith, redesigned...

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  • Accelerate your assay development using the enhanced Binding Check module in Monolith's MO.Control 2 software

    Accelerate your assay development using the enhanced Binding Check module in Monolith's MO.Control 2 software

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  • Advanced features in the new Monolith

    Advanced features in the new Monolith

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  • Scientists choose Monolith as their primary tool to measure binding interactions2:04

    Scientists choose Monolith as their primary tool to measure binding interactions

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  • When binding affinity matters.

    When binding affinity matters.

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  • The researcher’s guide to measuring binding affinity and why it matters

    The researcher’s guide to measuring binding affinity and why it matters

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  • The NanoTemper Story – Chapter 2: The Monolith

    The NanoTemper Story – Chapter 2: The Monolith

    It’s late at night in Munich, Germany sometime in the late 2000’s. A man huddles in a dimly lit basement, painting. He paints at night after a complaint from the professors upstairs about the...

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  • The importance of molecular interactions and stability in Gene Therapy46:44

    The importance of molecular interactions and stability in Gene Therapy

    New advances in gene therapy have triggered a resurgence of interest in the field. Though gene therapy offers exciting potential for the treatment of both monogenic disorders as well as more genetical

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  • Isoform-Selective ATAD2 chemical probe with novel chemical structure and unusual mode of action

    Isoform-Selective ATAD2 chemical probe with novel chemical structure and unusual mode of action

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  • 4 studies highlight the impact of biophysical tools in plant science research

    4 studies highlight the impact of biophysical tools in plant science research

    Plant research paves the way for important advances in agriculture, ecology, and medicine. As an example, discoveries into plant pathogens and plant stress response lead to many incremental...

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  • Trends and challenges in glycobiology: Biophysical tools to advance your molecular studies17:10

    Trends and challenges in glycobiology: Biophysical tools to advance your molecular studies

    The prominent role of glycans in biomedical research is exponentially raising as researchers discover how these sugars deeply affect protein structure and function.

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  • Have a question about Monolith?

    Contact Specialist
  • What these 3 publications uncovered about coronavirus protein structures using MST

    What these 3 publications uncovered about coronavirus protein structures using MST

    Coronaviruses (CoV) have been responsible for multiple outbreaks this century. The COVID-19 pandemic — caused by the novel SARS-CoV-2 coronavirus — has led to a global health, social, and economic...

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  • Site-specific covalent labeling of SNAP-tagged proteins for the measurement of binding affinities

    Site-specific covalent labeling of SNAP-tagged proteins for the measurement of binding affinities

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  • Solutions for Plant Science14:45

    Solutions for Plant Science

    As the population grows, our environment is changing and our natural resources are being depleted. That’s why research on plant production, temperature and pathogen resistance, environmental stress, p

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  • Antibody-targeted chromatin enables effective intracellular delivery and functionality of CRISPR/Cas9 expression plasmids

    Antibody-targeted chromatin enables effective intracellular delivery and functionality of CRISPR/Cas9 expression plasmids

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  • Did you say, “membrane proteins”? Challenge accepted!4:09

    Did you say, “membrane proteins”? Challenge accepted!

    Working with difficult targets like GPCRs and other membrane proteins? Because they live in the cell membrane, are hydrophobic and insoluble, have low expression levels, and require particular deter

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  • Measure molecular interactions in purification-free systems8:04

    Measure molecular interactions in purification-free systems

    In this short video, you will learn: -How labs are able to measure binding affinity in complex systems -Why it's important to look at binding affinity in complex bioliquids or in vivo -How to study mo

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  • Advance your understanding of neurodegenerative diseases

    Advance your understanding of neurodegenerative diseases

    Use this eBook to advance your own neurodegenerative diseases (ND) research by reading a selection of peer-reviewed publications. Find out how researchers are gaining insight into the molecular mechan

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