Optimizing stability during the formulation of therapeutic proteins
Monoclonal antibodies and therapeutic proteins for vaccines require extensive stability characterization during their development phase to improve their probability of successful treatment. We will discuss several case studies that demonstrate how the robust intrinsic fluorescence (nanoDSF) and dynamic light scattering (DLS) data obtained from NanoTemper’s Prometheus instruments helped many groups find better formulations and storage buffers to ultimately expedite the lab to clinic pipeline.