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Sizing accuracy and intra-assay precision of DLS measurements with Prometheus Panta

November 13, 2020

Scientists in the field of drug discovery, particularly biologics, use DLS to make critical decisions about drug candidate stability. This creates a need for instruments that exhibit strong sizing accuracy and precision. These properties can be evaluated using standards and references from the National Institute of Standards and Technology (NIST). Here, the NIST monoclonal antibody (NISTmAb) reference material (RM) RM8671, Lysozyme, and a set of monodisperse particle size standards were used to test the sizing accuracy and intra-assay precision of Prometheus Panta’s DLS optical module.

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Measure binding affinities for any type of interaction — examine a label-free or labeled target molecule at anytime
Measure binding affinities for any type of interaction — examine a label-free or labeled target molecule at anytime

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Accelerate your assay development using the enhanced Binding Check module in Monolith's MO.Control 2 software
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