One major benefit of the Prometheus instruments is that they acquire high-quality thermal stability data of proteins using a minimal number of handling steps. Specifically, the patented capillary format (DE102014018535A1) allows for sample loading without pipetting steps, simply by dipping the capillaries into the protein solution. Moreover, the design of the thermal element in combination with the capillary sample format enables measurements of thermal unfolding curves with unsealed capillaries, which means that no additional handling steps are required between the filling of the capillary with the sample and loading it into the instrument. This makes the Prometheus instrument one of the most simple, straightforward and time-saving analytical instruments available.
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Most recent content
Validation of Tycho NT.6 precision and repeatability
Protein labeling – improved quantitation of biomolecular interactions by MST using the His-Tag labeling kit RED-tris-NTA 2nd generation
Monitoring the impact of storage-dependent denaturation on protein quality using Tycho NT.6
Repeatability assessment of Tycho NT.6 for better protein quality checks
Validation of protein complex functionality with Tycho NT.6
Quick protein binding analysis by label-free thermal shift analysis on the Tycho NT.6
Better optimization of biosensor assay development with Tycho NT.6
Evaluation of slow equilibration kinetics in antibody chemical denaturation experiments
Evaluating unfolding reversibility using temperature cycle measurements
Precision of measurements with the Prometheus NT.48