NanoTemper Technologies launches DLS capability with Prometheus Panta, bringing high-resolution, domain-specific stability characterization

September 23, 2020 NanoTemper Technologies

Prometheus Panta


SOUTH SAN FRANCISCO, Calif., September 24, 2020 – NanoTemper Technologies, well-known for creating tools that address challenging characterizations, today introduced Prometheus Panta, a multi-parameter stability characterization instrument. By combining DLS for particle size determination with nanoDSF for thermal unfolding and backreflection for aggregation, researchers in biologics formulation optimization, developability, or comparability assessments will find that Prometheus Panta offers superior characterization of their candidate molecules.


“Inevitably, researchers will come across candidate molecules that present challenges. Here’s where Prometheus Panta shines, offering a solution they can rely on for clear, trustworthy, and high-resolution data for colloidal and conformational stability,”
said Philipp Baaske, Co-CEO of NanoTemper.


Having the right technology really matters when researchers need to detect small differences or subtleties in unfolding events. Missing these details means handing over subpar candidates to teams working downstream — a costly mistake for drug pipelines.


“For the first time, researchers are able to correlate particle sizing, thermal unfolding and aggregation results collected throughout an entire thermal ramp,”
comments Charles Heffern, Product Manager at NanoTemper.


“This gives them a completely new perspective about stability attributes at the domain level that they would’ve otherwise missed.” Getting clear answers to questions — Which domains have a tendency to aggregate and at what temperature does this happen? Is the increase in particle size at a certain temperature due to an unfolding event for a particular domain? — are now possible.

Visit to find out more details. For the most up-to-date information, follow NanoTemper on LinkedIn, Facebook, and Twitter.


About NanoTemper Technologies

Our mission at NanoTemper Technologies is to enable everyone to do science that matters by always pushing the limits. We’re focused on making tools that address challenging characterizations for use in drug discovery and basic science research. Working with scientists striving to make a difference in the world gets us excited. If you’re facing challenges with affinity screening, molecular interactions, protein stability, or protein quality, let’s talk.


Jocelyn Davé

Previous Article
Characterize the true nature of intrinsically disordered proteins without immobilizing them
Characterize the true nature of intrinsically disordered proteins without immobilizing them

If you study neurodegenerative diseases (ND), you already know they are one of the most challenging — and f...

Up next
Seven tips to give your grant proposal that extra edge
Seven tips to give your grant proposal that extra edge

Grant writing is an important bread-and-butter skill that all principal investigators must develop, as this...

Have a question?

Contact Specialist

Sign up to receive
the latest NanoTemper news, product updates, event announcements and more

First Name
Last Name
Company Name
Agree to Subscribe & Privacy Policy*
*I have fully read, understood and agree to the Privacy Policy. I accept the storing and processing of my personal data by NanoTemper as described in the Privacy Policy.

By completing this form, you provide us consent to contact you with educational content, news and information about our products, services and events. You may unsubscribe at any time.
Thank you!
Error - something went wrong!