×

You're seconds away from this application note!

First Name
Last Name
Company Name
Country
State
Province
State
Region
State
Canton
Agree to Privacy Policy*
*I have fully read, understood and agree to the Privacy Policy. I accept the storing and processing of my personal data by NanoTemper as described in the Privacy Policy.
Thank you!
Error - something went wrong!
   

Binding of calcium ions to synaptotagmin measured with fluorescence label and label-free

The synaptic vesicle protein synaptotagmin 1 is the main calcium sensor of neuronal exocytosis. Calcium binds to its cytosolic portion that consists of tandem C2-type domains. In this work we show that Microscale Thermophoresis is a valuable tool to measure binding of ions to proteins, with and without the use of a fluorescent label.

Previous
Binding of histone peptides to chromatin assembly factor I (CAF-I) p48 subunit
Binding of histone peptides to chromatin assembly factor I (CAF-I) p48 subunit

Up next
Competitive Assay Approach: Binding of Small Molecules to the Active Form of p38
Competitive Assay Approach: Binding of Small Molecules to the Active Form of p38

Have a question about Monolith?

Contact Specialist