Tackle small molecule drug discovery screening challenges with Dianthus

Bifunctional degrader molecules (also known as PROTACs) and molecular glues recruit proteins to E3 ubiquitin ligases. The formation of a ternary complex between PROTAC, ligase, and the protein of inte

The stability of biopharmaceuticals is a complex mixture of parameters and plays a crucial role throughout the entire product lifecycle, from discovery through production and manufacturing. Making cri

Stability of biopharmaceuticals is a complex matrix of parameters that plays a crucial role through the entire product life-cycle. Through case studies, we discuss how Prometheus provides clarity by d

The prominent role of glycans in biomedical research is exponentially raising as researchers discover how these sugars deeply affect protein structure and function.

Development of therapeutic antibodies is a long and costly process. One key indicator of whether biologic candidates will be successful is stability. Prometheus enables rapid and precise characterizat

New advances in gene therapy have triggered a resurgence of interest in the field. Though gene therapy offers exciting potential for the treatment of both monogenic disorders as well as more genetical

There are a number of interesting drug targets that have a reputation of being especially difficult to study in biochemical or biophysical assays. Join us to learn how Dianthus can help you address t

Neurodegenerative diseases like Alzheimer’s or Parkinson’s Disease affect millions of people worldwide. Although current treatments may help relieve some of the physical or mental symptoms, there is s

Pandemics have affected human society throughout history, but with the current pandemic happening today, realization is quickly setting in just how much viral infectious diseases impact everyday life.

Gene therapy—a type of DNA-based medicine that utilizes a virus to insert a healthy gene into cells to replace a mutated, disease-causing variant has emerged as one of the most promising medical treat

How do you usually know whether your protein is happy? Even if you’re already using a portfolio of techniques to check, you may not have all the info. Find out how to use Tycho to really understand wh

This therapeutic antibody drug development webinar discusses the idea of limiting the substantial investment of time, money, or resources.

Vaccines are biological products derived from living organisms that provide an immune response to pathogens or diseases.While research efforts in developing vaccines continue to increase, scientists

Cellular expression and purification of proteins are among the most widely used techniques in biology. Expressing proteins in stable, properly-folded states is a challenge that may be abated by monito

Process development for Fill & Finish activities of large molecule parenterals requires an orchestrated effort of multiple functions to deal with product specific critical quality attributes (CQAs) an

Analyzing large amounts of experimental data is as big a bottleneck in your workflow as running the experiments themselves. Struggling through manual manipulation of data or complex third-party softwa

Influenza A virus (IAV) utilizes a multivalent binding strategy to the host cell, binding its trimeric spike protein hemagglutinin (HA) to sialic acid present on the cellular membrane. For this reason