Surface plasmon resonance (SPR) is an optical methodology used to detect and quantify molecular interactions. Although SPR is widely used and considered by many researchers to be the gold standard for quantification of protein interactions, assay optimization can be technically challenging, time-consuming and costly. The Tycho NT.6 system quickly analyzes different conditions typically tested when optimizing an SPR assay. It utilizes very small amounts of sample and provides dramatic time and cost savings compared to standard SPR assay development procedures. Tycho NT.6 is simple to use and enables researchers to make better educated decisions in developing and optimizing their binding interaction assays.
See more related content
The NanoTemper Story – Chapter 4: The Tycho
The Tycho was developed to help protein researchers better understand how their proteins are behaving. The Prometheus is great for advanced biophysical characterization, but sometimes all a...
Capsid lattice destabilization leads to premature loss of the viral genome and integrase enzyme during HIV-1 infection
4 SPR assay problems that can be resolved by improving protein quality
Surely you’ve found yourself in a research situation where your experimental results left you scratching your head. Any type of lab work will sometimes do that to you, and Surface Plasmon...
Why you should consider subscribing to research instruments instead of buying
In recent years, subscriptions have become more and more popular. Chances are you have some too — maybe you have a subscription to your favorite video or music streaming service, or you have a...
45:48Cellular expression and purification of proteins are among the most widely used techniques in biology. Expressing proteins in stable, properly-folded states is a challenge that may be abated by monito
5 publications that put protein quality checks into the workflow, using Tycho
By providing a better understanding of the quality of their samples, Tycho helped prevent unnecessary experiments, minimize questionable data, and change how scientists approach experiments. Here...
Cyrill Brunner gets Explorer Award for innovative approach to advance drug discovery research using computer modeling
Meet Cyrill Brunner, Senior PhD candidate at ETH in Zurich, Switzerland (preparing to defend his thesis as we go to press) and one of the 2019 Explorer award recipients. This award is given to...
What you wish you knew before storing your protein in the freezer
Contrary to what many researchers may think, there is no universal storage practice that can be applied to all proteins that ensure their integrity will indefinitely be maintained. In fact,...
3 ways to know your protein purification is a success
With any experiment, it’s important to standardize the steps to ensure consistent results. Let’s take a look at three metrics that are commonly monitored and should be measured during any protein...
Tycho named one of the Top 10 Innovations of 2018 by The Scientist
We’re thrilled that Tycho is named one of the winners in The Scientist's Top 10 Innovations of 2018 contest. We’re even further honored that the panel of independent judges — who represent the...