Tycho | Protein Quality

The NanoTemper Story – Chapter 4: The Tycho

What would you do if you created a brilliant new invention, but no one knew or understood why they would use it? You know that it would change the way everyone works and lives, but you need to...

How to confirm you’ve cooked perfect eggs, using scientific instruments

If you’ve been following my cooking and chemistry blog series, I hope you’ve enjoyed recaps of interesting lessons I learned from HarvardX’s course. For my last post in this series, I’m digging...

How to access your Tycho data from anywhere with Tycho.Cloud

Having the flexibility to work from anywhere is more important than ever, especially for researchers who are doing critical work. You may still need to access your lab instruments, but working...

How to look at your protein’s functionality and concentration with Tycho.Cloud

Whether you’re a Tycho.Cloud user or just hearing about it, the big vision for Tycho.Cloud and its current capabilities are focused on helping you get more out of your Tycho data and really...

4 SPR assay problems that can be resolved by improving protein quality

Surely you’ve found yourself in a research situation where your experimental results left you scratching your head. Any type of lab work will sometimes do that to you, and Surface Plasmon...

Why you should consider subscribing to research instruments instead of buying

In recent years, subscriptions have become more and more popular. Chances are you have some too — maybe you have a subscription to your favorite video or music streaming service, or you have a...

3 Tycho.Cloud apps that help you compare protein samples

Tycho gives you a better idea of what you’re working with by comparing your samples: Comparing a protein before and after storage, or comparing a protein in different buffers, or comparing the...

How the cloud will transform the way you do research

Imagine how your scientific research can be made easier Imagine this scenario: you run a binding affinity assay on, let’s say, NanoTemper’s Monolith, and instead of just a Kd result, you get...

Accelerate your protein purification workflow by knowing protein quality first

Protein quality is a challenging parameter to measure. Clearly, when the quality of a protein is poor, it likely won’t function and often can be difficult to even characterize. When questionable...

5 publications that put protein quality checks into the workflow, using Tycho

Tycho launched a little over two years ago in January 2018 as the solution for quickly assessing protein quality. Soon after, The Scientist journal even recognized Tycho as one of the top 10...

Cyrill Brunner gets Explorer Award for innovative approach to advance drug discovery research using computer modeling

Meet Cyrill Brunner, Senior PhD candidate at ETH in Zurich, Switzerland (preparing to defend his thesis as we go to press) and one of the 2019 Explorer award recipients. This award is given to...

3 assumptions from an SDS-PAGE that lead to false conclusions

What is an SDS-PAGE used for? Scientists who routinely analyze proteins turn to SDS-PAGE, a proven method for separating proteins and peptides based on their molecular weight. First reported in...

Thermal unfolding and refolding of a lytic polysaccharide monooxygenase from Thermoascus aurantiacus