Tycho | Protein Quality

Capsid lattice destabilization leads to premature loss of the viral genome and integrase enzyme during HIV-1 infection

4 SPR assay problems that can be resolved by improving protein quality

Surely you’ve found yourself in a research situation where your experimental results left you scratching your head. Any type of lab work will sometimes do that to you, and Surface Plasmon...

Why you should consider subscribing to research instruments instead of buying

In recent years, subscriptions have become more and more popular. Chances are you have some too — maybe you have a subscription to your favorite video or music streaming service, or you have a...

5 publications that put protein quality checks into the workflow, using Tycho

Tycho launched a little over two years ago in January 2018 as the solution for quickly assessing protein quality. Soon after, The Scientist journal even recognized Tycho as one of the top 10...

Cyrill Brunner gets Explorer Award for innovative approach to advance drug discovery research using computer modeling

Meet Cyrill Brunner, Senior PhD candidate at ETH in Zurich, Switzerland (preparing to defend his thesis as we go to press) and one of the 2019 Explorer award recipients. This award is given to...

Thermal unfolding and refolding of a lytic polysaccharide monooxygenase from Thermoascus aurantiacus

Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles

Molecular basis for the binding and selective dephosphorylation of Na+/H+ exchanger 1 by calcineurin

What you wish you knew before storing your protein in the freezer

Storing protein samples sounds like an easy thing to do in the lab. After all, you just put them in the freezer right? But is that all to it? Can all proteins withstand freezing (and thawing)...

Kinetic and structural analysis of human ALDH9A1

3 ways to know your protein purification is a success

Protein purification is a challenging endeavor for many scientists and it usually takes time and sweat to get to your end results. Calling a protein purification a success can mean something...

Tycho named one of the Top 10 Innovations of 2018 by The Scientist

We’re thrilled that Tycho is named one of the winners in The Scientist’s Top 10 Innovations of 2018 contest. We’re even further honored that the panel of independent judges — who represent the...