Tycho | Protein Quality
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The NanoTemper Story – Chapter 4: The Tycho
What would you do if you created a brilliant new invention, but no one knew or understood why they would use it? You know that it would change the way everyone works and lives, but you need to...
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Capsid lattice destabilization leads to premature loss of the viral genome and integrase enzyme during HIV-1 infection
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4 SPR assay problems that can be resolved by improving protein quality
Surely you’ve found yourself in a research situation where your experimental results left you scratching your head. Any type of lab work will sometimes do that to you, and Surface Plasmon...
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Why you should consider subscribing to research instruments instead of buying
In recent years, subscriptions have become more and more popular. Chances are you have some too — maybe you have a subscription to your favorite video or music streaming service, or you have a...
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Accelerating Protein Purification by Using Thermal Unfolding as a Guiding Tool
Cellular expression and purification of proteins are among the most widely used techniques in biology. Expressing proteins in stable, properly-folded states is a challenge that may be abated by monito
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5 publications that put protein quality checks into the workflow, using Tycho
Tycho launched a little over two years ago in January 2018 as the solution for quickly assessing protein quality. Soon after, The Scientist journal even recognized Tycho as one of the top 10...
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Cyrill Brunner gets Explorer Award for innovative approach to advance drug discovery research using computer modeling
Meet Cyrill Brunner, Senior PhD candidate at ETH in Zurich, Switzerland (preparing to defend his thesis as we go to press) and one of the 2019 Explorer award recipients. This award is given to...
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Thermal unfolding and refolding of a lytic polysaccharide monooxygenase from Thermoascus aurantiacus
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Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles
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Molecular basis for the binding and selective dephosphorylation of Na+/H+ exchanger 1 by calcineurin
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Validation of Tycho NT.6 precision and repeatability
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What you wish you knew before storing your protein in the freezer
Storing protein samples sounds like an easy thing to do in the lab. After all, you just put them in the freezer right? But is that all to it? Can all proteins withstand freezing (and thawing)...
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Kinetic and structural analysis of human ALDH9A1
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Validation of protein complex functionality with Tycho NT.6
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3 ways to know your protein purification is a success
Protein purification is a challenging endeavor for many scientists and it usually takes time and sweat to get to your end results. Calling a protein purification a success can mean something...
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Repeatability assessment of Tycho NT.6 for better protein quality checks
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Quick protein binding analysis by label-free thermal shift analysis on the Tycho NT.6
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Monitoring the impact of storage-dependent denaturation on protein quality using Tycho NT.6
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Tycho named one of the Top 10 Innovations of 2018 by The Scientist
We’re thrilled that Tycho is named one of the winners in The Scientist’s Top 10 Innovations of 2018 contest. We’re even further honored that the panel of independent judges — who represent the...
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Better optimization of biosensor assay development with Tycho NT.6
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