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Interactions of liposome embedded SNARE proteins

November 9, 2018

SNARE protein complexes play a key role in membrane fusion processes, e.g. the fusion of synaptic vesicles with the pre-synaptic plasma membrane in response to elevated Ca2+ levels. This study aimed to demonstrate the use of Microscale Thermophoresis for the detection of protein-protein interaction in more complex assay systems like in this case the interaction of membrane proteins embedded into liposomes.

Previous Article
Phosphorylation of human aquaporin 2 (AQP2) allosterically controls its interaction with the lysosomal trafficking protein LIP5
Phosphorylation of human aquaporin 2 (AQP2) allosterically controls its interaction with the lysosomal trafficking protein LIP5

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Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions
Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions

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