Sophisticated experiments with high information content for advanced protein stability testing, right at your fingertips!
Measure all your samples - virtually independent of concentration, type of protein, number of tryptophan residues and buffer conditions. Monitor conformational and colloidal stability simultaneously, using the same samples.
Choose between isothermal measurements, (incremental) temperature cycling, and temperature stepping. The straightforward, graphically guided interface guarantees easy assay setup - yet it enables sheer endless applications like analyses of shelf-life, manufacturability, developability, and formulation development.
Most recent content
15:19Virtual Monolith X Demo: Free-in-solution affinity measurements with minimal sample consumption
The tool you choose to measure affinities should tackle a diverse range of targets and ligands that come your way — such as GPCRs, IDPs, or cancer-related proteins. And, you should get data that help
0:40What are ADCs and how do they work against cancer?
In this short animated video, learn the basics of how antibody-drug conjugates (ADCs) are engineered and why that makes them such powerful tools to target cancers with precision.
12:54Dianthus is a biophysical screening instrument that uses Spectral Shift technology to measure molecular interactions for hit ID, hit-to-lead, and lead optimization. It offers a 384-well plate format a
4:51Four integrated technologies for biologics developability assessment
The decisions you make about your biologics candidates early in the pipeline ultimately affect their success as therapeutics. Combine sizing and stability information to develop successful biologics
9:42Virtual Prometheus Panta demo: Four integrated technologies for protein stability characterization
Your protein stability characterization projects require tools that provide high-precision, high-quality data to support your selection process. Watch this 10 min walkthrough of Prometheus Panta.
2:20Introducing Monolith X - the only way to get binding affinities in solution using very minimal sample
1:41Prometheus Panta: The new gold standard for biologics characterization
Choosing the right stability characterization tool for your biologics research is a big commitment. You’re going to be screening and optimizing lots of candidates, and you’ll need data on thermal stab
2:46Learn what attributes Prometheus users considered a must-have and how we made sure to preserve them when integrating and implementing new biophysical techniques. Prometheus Panta gives you the ability
2:34Discover how 2bind applied multi-parameter characterization from a single experiment to find the optimal buffer for a vaccine antigen target.
14:07When you develop an AAV therapeutic, you need to assess many key parameters, or Critical Quality Attributes (CQAs), in order to track progress and, ultimately, get your therapeutic approved. As part
1:31How Janssen optimizes the stability of a therapeutic mAb
Discover how Janssen improved the stability of a promising prostate cancer targeting mAb. You’ll learn why it is important to optimize stability measurements of a therapeutic mAb.
1:39How Coriolis Pharma screens a vast chemical library for stabilizing excipients
Discover how Coriolis Pharma found the best excipients to stabilize their monoclonal antibodies for long-term storage. You’ll learn about the importance of expanding the chemical space for excipients
3:59PR.Stability Analysis offers a great feature to dramatically reduce the amount of time you spend processing your Prometheus data. With Key Parameters, it is possible to quickly and reliably calculate
4:06PR.Stability Analysis software offers a great new feature—Percent Similarity— that is used to analyze how your formulations and preparations compare to earlier experiments. It enables you to get quant
4:36Data analysis is a challenging process—researchers have mountains of data to go through—and expediting analysis with automated software solutions is a crucial tool to save you time and effort. However
4:20Personalize your data by adding and removing markers in your datasets using PR.Stability Analysis software When looking at large data sets, it is not easy to go through each individual unfolding curv
5:55Anyone who has ever worked in a lab has heard the same refrain in some context or another – “We need more data!" No matter how many experiments you do, it feels like reviewers, regulators, or even you
4:09Working with difficult targets like GPCRs and other membrane proteins? Because they live in the cell membrane, are hydrophobic and insoluble, have low expression levels, and require particular deter
5:02The scientific method can be a long, arduous process, but there are many tools available to researchers to make data analysis less daunting. PR.Stability Analysis software was designed to enable Prom