Targeted protein degradation promises to lead the way to effective drugs for challenging targets

May 7, 2021

Researchers are using targeted protein degradation as a strategy to develop drugs that target disease-causing proteins where traditional inhibitor drugs can’t be used. 

In this infographic, we discuss both inhibition and degradation, the advantages and challenges related to each approach, and the key points you need to consider when designing your protein degraders. 

 

Learn how researchers are using NanoTemper tools to evaluate the affinity and specificity of their PROTAC candidate. 

Previous Article
MST and TRIC technology to reliably study PROTAC binary and ternary binding in drug development
MST and TRIC technology to reliably study PROTAC binary and ternary binding in drug development

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Improve your protein degrader design with new ways to discover E3 ligase ligands
Improve your protein degrader design with new ways to discover E3 ligase ligands

Targeted protein degradation using molecular glues or proteolysis-targeting chimeras (PROTACs) is an increa...

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