Learn the pros and cons of these 3 methods to serotype your AAV gene therapy vectors
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5 benefits of optimizing your formulation buffer to get your AAV therapeutic approved
As a gene therapy scientist, you face an abundance of challenges when working to build an effective AAV therapeutic. Many steps of the development workflow have yet to be standardized and the...
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Serotyping: why, when, and how to assess your AAV therapeutic to get it approved
When you develop an AAV therapeutic, you need to assess many key parameters, or Critical Quality Attributes (CQAs), in order to track progress and, ultimately, get your therapeutic approved.
As part
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8 Gene Therapy conferences you should attend in 2022
With the first AAV-based gene therapies approved, and new gene editing strategies emerging, it’s important to stay on top of the latest topics in this therapeutic area. Here are 8 gene therapy...
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Ways light scattering technologies help you if you’re in gene therapy
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NanoTemper Technologies arms gene therapy scientists with Static Light Scattering to sharpen their tool kit for development of AAVs
SOUTH SAN FRANCISCO, Calif Feb 16 2022 — NanoTemper Technologies today announced the addition of Static Light Scattering (SLS) to their wildly successful Prometheus Panta, turning their instrument...
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How to improve outcomes of your viral vectors for gene therapy with high-quality data from biophysical profiling methods
Optimizing your vectors for gene therapy is a daunting task. When developing and optimizing AAVs, concerns such as serotype, storage stability, expression method, and genetic fill level must be addres
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Methods Matter: Standard production platforms for recombinant AAV produce chemically and functionally distinct vectors
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Quantitation of trace levels of DNA released from disrupted Adeno-associated virus gene therapy vectors
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Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing
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Antibody-targeted chromatin enables effective intracellular delivery and functionality of CRISPR/Cas9 expression plasmids
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Intrinsic differential scanning fluorimetry for fast and easy identification of Adeno-Associated Virus serotypes
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Humanized Selective CD19CAR-T Cells Treatment Shows Efficacy in B-ALL Patients Who Relapsed after Receiving Murine-Based CD19CAR-T Therapies
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Spatial screening of hemagglutinin on Influenza A Virus particles: Sialyl-LacNAc displays on DNA and PEG scaffolds reveal requirements
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