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Sizing accuracy and intra-assay precision of DLS measurements with Prometheus Panta

November 13, 2020

Scientists in the field of drug discovery, particularly biologics, use DLS to make critical decisions about drug candidate stability. This creates a need for instruments that exhibit strong sizing accuracy and precision. These properties can be evaluated using standards and references from the National Institute of Standards and Technology (NIST). Here, the NIST monoclonal antibody (NISTmAb) reference material (RM) RM8671, Lysozyme, and a set of monodisperse particle size standards were used to test the sizing accuracy and intra-assay precision of Prometheus Panta’s DLS optical module.

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The definitive guide to understanding protein stability
The definitive guide to understanding protein stability

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Formulation and stability screening of biotherapeutics
Formulation and stability screening of biotherapeutics

The stability of biopharmaceuticals is a complex mixture of parameters and plays a crucial role throughout ...

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