Multi-parameter formulation development for an HIV-vaccine protein with direct validation of epitope binding

Join Thomas Schubert, CEO of 2bind, as he walks through experiments done on the Prometheus Panta to determine the optimal buffer for a vaccine candidate. This HIV-derived protein is used as an antigen target for vaccine development, and it is crucial that this target is stored in a buffer that reduces aggregation and enhances long-term stability. Learn how 2bind used Prometheus Panta to do a 96-condition buffer screen, find the optimal buffer for stability in standard and stressed conditions, and validate antibody binding to the antigen — all in one instrument.

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The autocorrelation function: the key to understanding your biological molecules
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Rapid development of SARS-CoV-2 spike protein receptor-binding domain self-assembled nanoparticle vaccine candidates
Rapid development of SARS-CoV-2 spike protein receptor-binding domain self-assembled nanoparticle vaccine candidates

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