When developing an antibody drug conjugate (ADC), scientists rely on stability experiments using fluorescence and light scattering techniques to get predictive insights into the conjugated molecule's behavior downstream, during optimization and delivery.
Collecting this information early in the development process is valuable to prevent stability issues during long-term storage or for high-concentration administration of the ADC. Watch this webinar to discover the Prometheus Panta instrument and how it supports several stability prediction experiments to give you confidence in the stability characteristics of your ADC candidates.
You'll learn:
- How to set up and interpret self-association experiments that provide insight into how your biologics will behave at clinically-relevant concentrations
- How thermal unfolding information from nanoDSF is used to measure kinetic stability, and make predictions about long-term storage stability
- Why these predictive stability experiments are so critical to undertake early in the development process
Explore the topic of ADC stability characterization with related resources:
- Webinar: How to mitigate risk during ADC development with multi-parameter stability characterization
- Blog: De-risk your ADC development process with these stability considerations
To learn more about tools for stability assessment of ADCs, meet Prometheus Panta.
