Measuring protein stability is necessary for numerous applications from understanding the molecular basis for certain diseases to developing more effective drugs. Whether you’re just starting to learn about characterizing a protein’s stability or you’re looking for a refresher, this guide has some helpful tips to answer why it’s important, what technologies are available and how to thoroughly evaluate them before purchasing.
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2:43Prometheus has been tested, validated and chosen by leading researchers around the world as the go to instrument for characterizing protein stability. Rapidly get the most precise results on stability
The NanoTemper Story – Chapter 3: The Prometheus
By 2014, NanoTemper had won a slew of awards for the Monolith. Labs throughout Europe were using MST to measure their biological interactions, and the technology was starting to catch on...
17:36Stability of biopharmaceuticals is a complex matrix of parameters that plays a crucial role through the entire product life-cycle. Through case studies, we discuss how Prometheus provides clarity by d
nanoDSF: In vitro label-free method to monitor Picornavirus uncoating and test compounds affecting particle stability
5 of our favorite resources for studying protein stability
Proper assessment of protein stability is not only worthwhile but necessary. Those who carefully evaluate the quality of their protein samples and optimize preparative workflows improve their...
17:10The prominent role of glycans in biomedical research is exponentially raising as researchers discover how these sugars deeply affect protein structure and function.
4 studies highlight the impact of biophysical tools in plant science research
Plant research paves the way for important advances in agriculture, ecology, and medicine. As an example, discoveries into plant pathogens and plant stress response lead to many incremental...
30:05The new gold standard in biologic characterization – Develop your biologics faster and better with Prometheus
Development of therapeutic antibodies is a long and costly process. One key indicator of whether biologic candidates will be successful is stability. Prometheus enables rapid and precise characterizat
How to export your data and set export templates in PR.Stability Analysis software
As you become an expert in analysis with your Prometheus data, you will start to streamline your analysis process. Building large datasets is important for many workflows, whether you work on...
Compare your datasets with ease using percent similarity profiles in PR.Stability Analysis software
Developing good scientific research is a long process. You start with a hypothesis, conduct experiments to support it, and draw conclusions from there. But the process is iterative—every question...
4:06PR.Stability Analysis software offers a great new feature—Percent Similarity— that is used to analyze how your formulations and preparations compare to earlier experiments. It enables you to get quant
Personalize your data by adding and removing markers in your datasets using PR.Stability Analysis software
Thermal unfolding data is an easy way to create a “fingerprint” of your protein. By keeping the same ramp rate, you can compare how the unfolding of a single protein changes in response to...
4:36Data analysis is a challenging process—researchers have mountains of data to go through—and expediting analysis with automated software solutions is a crucial tool to save you time and effort. However
Become an expert in analyzing your Prometheus data in the PR.Stability Analysis software
Anyone who has ever worked in a lab has heard the same refrain in some context or another – “We need more data!” No matter how many experiments you do, it feels like reviewers, regulators, or even...
4:20Personalize your data by adding and removing markers in your datasets using PR.Stability Analysis software When looking at large data sets, it is not easy to go through each individual unfolding curv