Melting temperature (Tm) is a popular stability assessment parameter for therapeutic proteins like antibodies because it is quick and easy to measure compared to most other developability characteristics. Though there are different methodologies for finding Tm, all require fairly low sample volumes and conduct a measurement within a working day.
In this table, learn some of the additional considerations around 4 different methods for thermal stability assessment of therapeutic proteins.
While each provides unique value, the table will help you understand why nanoDSF is the go-to choice for determining the Tms of your therapeutic proteins.
