Application Notes

Ultra-high-throughput biophysical screening of MEK1 using the Dianthus uHTS platform

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2 0 A P P L I C A T I O N N O T E The Dianthus uHTS platform successfully identified and characterized potential potent MEK1 binders in a high-throughput manner. The integration of dose-response analysis and thermal shi assays enabled efficient hit validation, supporting its use in early-stage drug discovery. C O N F L I C T O F I N T E R E S T IJ, VH, JS and NBPA are employees of NanoTemper Technologies GmbH Conclusion

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