Application Notes

Ultra-high-throughput biophysical screening of MEK1 using the Dianthus uHTS platform

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1 9 A P P L I C A T I O N N O T E Figure 9. A. Waffle plot of hits from primar y screen to follow up estimated affinities. B. Venn diagram of Prio1 hits after characterization by Affinity Titration, Thermal Shift Assay (∆T m ) and ADP Glo (Kinase Inihibitors). C. Comparison of the Spectral Shift and ADP Glo workflows.

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