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2 1 A P P L I C A T I O N N O T E References [1] A. Langer et al., "A New Spectral Shi-Based Method to Characterize Molecular Interactions," Assay Drug Dev Technol, vol. 20, no. 2, pp. 83–94, Mar. 2022, doi: 10.1089/adt.2021.133. [2] S. Nishikawa, H. Watanabe, N. Terasaka, T. Katoh, and K. Fujishima, "De Novo Single-Stranded RNA-Binding Peptides Discovered by Codon-Restricted mRNA Display," Biomacromolecules, vol. 25, no. 1, pp. 355–365, Jan. 2024, doi: 10.1021/acs.biomac.3c01024. [3] M. P. Schwalm et al., "Critical assessment of LC3/GABARAP ligands used for degrader development and ligand- ability of LC3/GABARAP binding pockets," Nat Commun, vol. 15, no. 1, p. 10204, Nov. 2024, doi: 10.1038/s41467-024- 54409-5. [4] D. Zian et al., "The efficiency of high-throughput screening (HTS) and in-silico data analysis during medical emergencies: Identification of effective antiviral 3CLpro inhibitors," Antiviral Res, vol. 237, p. 106119, May 2025, doi: 10.1016/j.antiviral.2025.106119. [5] H. J. Bailey et al., "An engineered cereblon optimized for high-throughput screening and molecular glue discov- ery," Cell Chem Biol, vol. 32, no. 2, pp. 363-376.e10, Feb. 2025, doi: 10.1016/j.chembiol.2024.11.002. [6] C. Legros, V. Porkolab, M. Sigoillot, and O. Mirguet, "Abstract 3094: Biophysics in kinase drug discovery programs: Spectral Shitechnology from fragment screening to mechanism of action," Cancer Res, vol. 84, no. 6_Supplement, pp. 3094–3094, Mar. 2024, doi: 10.1158/1538-7445.AM2024-3094. [7] É. Kiss et al., "Chlorophyll biosynthesis under the control of arginine metabolism," Cell Rep, vol. 42, no. 11, p. 113265, Nov. 2023, doi: 10.1016/j.celrep.2023.113265. [8] N. P. Coussens, J. C. Braisted, T. Peryea, G. S. Sittampalam, A. Simeonov, and M. D. Hall, "Small-Molecule Screens: A Gateway to Cancer Therapeutic Agents with Case Studies of Food and Drug Administration–Approved Drugs," Pharma- col Rev, vol. 69, no. 4, pp. 479–496, Oct. 2017, doi: 10.1124/pr.117.013755. [9] I. Rothenaigner and K. Hadian, "Brief Guide: Experimental Strategies for High-Quality Hit Selection from Small-Molecule Screening Campaigns," Aug. 01, 2021, SAGE Publications Inc. doi: 10.1177/24725552211008862.