40
Dispersity refers to how many different size
populations are present in a sample, and how
spread out those populations are around the
sample's mean value. The PDI values indicate how
homogenous the particle sizes in your solution are.
The values are derived from the autocorrelation
function fit (see Page 32).
What does dispersity tell me about my sample quality?
Monodispersity refers to a solution that has a single particle type,
with tight distribution around the mean r
H
. In essence, a highly
monodisperse sample means every particle in solution is uniformly
folded and in the same conformation and oligomerization state.
Intensity
distribution
[%]
r
H
Monodisperse
Dispersity
