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Dynamic light scattering, or DLS, is a way of measuring particle size, oligomerization, and dispersity, and
how they change in response to environmental changes like the addition of a drug conjugate or storage
buffer modifications.
During the course of Biologics development, DLS is a valuable tool for profiling how candidates behave
in response to a variety of environmental changes. Understanding the impact these changes have on
a candidate is crucial to many aspects of the biologics workflow, from determining which are worth
pursuing to improving their quality for scale-up and delivery.
This eBook explains how DLS helps improve the decisions you make about your biologics during the
entire workflow, as well as some practical tips for designing DLS experiments. In this book, you will learn:
• What biologics are and why they're important
• How DLS gives you information about your samples, and what that data means
• Tips and considerations when designing your own DLS experiments
You can read this entire book as a holistic approach to DLS as a part of the biologics workflow, or jump
straight to the section that is most relevant to your needs. Find out how DLS can meet the demand for
rigorous biophysical data necessary for the ultimate clinical success of your biologics candidates.
About this eBook
