eBooks & Guides

The biologics researcher's guide to DLS

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Page 1 of 63

2 Dynamic light scattering, or DLS, is a way of measuring particle size, oligomerization, and dispersity, and how they change in response to environmental changes like the addition of a drug conjugate or storage buffer modifications. During the course of Biologics development, DLS is a valuable tool for profiling how candidates behave in response to a variety of environmental changes. Understanding the impact these changes have on a candidate is crucial to many aspects of the biologics workflow, from determining which are worth pursuing to improving their quality for scale-up and delivery. This eBook explains how DLS helps improve the decisions you make about your biologics during the entire workflow, as well as some practical tips for designing DLS experiments. In this book, you will learn: • What biologics are and why they're important • How DLS gives you information about your samples, and what that data means • Tips and considerations when designing your own DLS experiments You can read this entire book as a holistic approach to DLS as a part of the biologics workflow, or jump straight to the section that is most relevant to your needs. Find out how DLS can meet the demand for rigorous biophysical data necessary for the ultimate clinical success of your biologics candidates. About this eBook

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