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NanoTemper Dianthus Brochure

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Do more than screening Little did you know that Dianthus is capable of doing more than just hit ID and validation. Because it handles a wide range of targets and has flexible throughput, it's so easy to choose Dianthus as your primary tool to characterize molecular interactions for a variety of applications. Choose the right system for you Characterize binding events to understand biological processes and structure-function relationships Analyze how multimeric proteins, GPCRs or aptamers interact with their ligands Support and confirm X-ray crystallography and Cryo-EM findings Perform competition assays in the presence of inhibitors nanotempertech.com/dianthus Dianthus NT.23 Dianthus NT.23Pico Dianthus NT.23PicoDuo Detected molecule range Molecular weight: 10 1 -10 7 Daltons Size: 0.1 nm – 1 µm Minimum sample volume 20 µL Affinity range nM to mM pM to mM Run time for 384 data points 60 min 30 min Format 384-well plate (barcoded and sealable) Fluorescence channels 1 (Red) 1 (Pico red) 2 (Pico red) Temperature control 20-25°C Dimensions 60cm W x 40cm H x 55cm D Dianthus NT.23 Dianthus NT.23Pico Dianthus NT.23PicoDuo Automation Option to integrate with liquid handlers and robotics Walk-away time (using 50-plate feeder) 50 hrs 25 hrs Compounds tested in 24 h single-dose in duplicate ~4150 ~8300 K d s measured in 24 h 12-pt dilution series ~750 ~1500 Dianthus is a trademark of NanoTemper Technologies GmbH, Munich, Germany. NanoTemper is a registered trademark of NanoTemper Technologies GmbH, Munich, Germany. ©2019 NanoTemper Technologies, Inc. South San Francisco, CA, USA. All Rights Reserved. BR-DI-01-2019-02

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