When studying neurodegenerative diseases you probably encounter technical challenges that come from working with proteins that aggregate or are intrinsically disordered. With NanoTemper’s tools you overcome these difficulties and start getting results.
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2:54Start getting consistent results by knowing protein quality with Tycho
Finding out the quality of your protein sample upfront will help you figure out if it’s functional, similar to a previous batch you made or if it’s been properly stored. With very little effort and a
The NanoTemper Story – Chapter 4: The Tycho
What would you do if you created a brilliant new invention, but no one knew or understood why they would use it? You know that it would change the way everyone works and lives, but you need to...
How to confirm you’ve cooked perfect eggs, using scientific instruments
If you’ve been following my cooking and chemistry blog series, I hope you’ve enjoyed recaps of interesting lessons I learned from HarvardX’s course. For my last post in this series, I’m digging...
How to access your Tycho data from anywhere with Tycho.Cloud
Having the flexibility to work from anywhere is more important than ever, especially for researchers who are doing critical work. You may still need to access your lab instruments, but working...
How to look at your protein’s functionality and concentration with Tycho.Cloud
Whether you’re a Tycho.Cloud user or just hearing about it, the big vision for Tycho.Cloud and its current capabilities are focused on helping you get more out of your Tycho data and really...
36:31How do you usually know whether your protein is happy? Even if you’re already using a portfolio of techniques to check, you may not have all the info. Find out how to use Tycho to really understand wh
4 SPR assay problems that can be resolved by improving protein quality
Surely you’ve found yourself in a research situation where your experimental results left you scratching your head. Any type of lab work will sometimes do that to you, and Surface Plasmon...
Why you should consider subscribing to research instruments instead of buying
In recent years, subscriptions have become more and more popular. Chances are you have some too — maybe you have a subscription to your favorite video or music streaming service, or you have a...
45:48Cellular expression and purification of proteins are among the most widely used techniques in biology. Expressing proteins in stable, properly-folded states is a challenge that may be abated by monito
3 Tycho.Cloud apps that help you compare protein samples
Tycho gives you a better idea of what you’re working with by comparing your samples: Comparing a protein before and after storage, or comparing a protein in different buffers, or comparing the...
Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity nanobody
How the cloud will transform the way you do research
Imagine how your scientific research can be made easier Imagine this scenario: you run a binding affinity assay on, let’s say, NanoTemper’s Monolith, and instead of just a Kd result, you get...
Accelerate your protein purification workflow by knowing protein quality first
Protein quality is a challenging parameter to measure. Clearly, when the quality of a protein is poor, it likely won’t function and often can be difficult to even characterize. When questionable...
5 publications that put protein quality checks into the workflow, using Tycho
Tycho launched a little over two years ago in January 2018 as the solution for quickly assessing protein quality. Soon after, The Scientist journal even recognized Tycho as one of the top 10...
Cyrill Brunner gets Explorer Award for innovative approach to advance drug discovery research using computer modeling
Meet Cyrill Brunner, Senior PhD candidate at ETH in Zurich, Switzerland (preparing to defend his thesis as we go to press) and one of the 2019 Explorer award recipients. This award is given to...
3 assumptions from an SDS-PAGE that lead to false conclusions
What is an SDS-PAGE used for? Scientists who routinely analyze proteins turn to SDS-PAGE, a proven method for separating proteins and peptides based on their molecular weight. First reported in...
