During early development of biologics, there are a large number of attributes researchers evaluate, but some of the most common center around stability – asking if a biologic is well-folded, active, and pure in its buffer, and whether it remains that way over time.
Biophysical characterization measurements from nanoDSF, DLS, backreflection, and SLS are valuable for providing this information without using a lot of material.
Read more to see how each of these technologies is helpful for characterization of your candidates during biologic development prior to clinical trials.