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Binding Affinity Explained - Your guide to understand, evaluate, and purchase the best solution for your lab.

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23 If you are the person taking the lead on purchasing the equipment for your lab, the first question to ask is: How much will it cost? Some offerings include the instrument only, but others may include as well the so ware, and in some cases, they'll include consumables and/or training, too. To get a sense of the total cost of investment, including upfront and ongoing costs, ask vendors what is included and not included in the quote they give you. Next, you need to find the necessary budget. Your institution may already have a process in place for purchasing new capital equipment, in which case you may be able to use money that has been set aside previously. Alternatively, you can factor in your new equipment purchase as part of a new budget for the following year. Depending on how the purchasing process works at your organization, you may need to involve a lab manager or procurement officer. Find out what kind of documentation you need to provide to gain approval. Your funding source for new equipment will vary depending on if you are in academia or industry. At a university, you can apply for a grant to fund the purchase. Also, you may receive support from external sources that are interested in funding your research. These external sources include foundations or collaborations with other groups that have similar interests. To make the purchase more affordable, consider splitting it with other groups at your institution who share your interests and have extra funding. Or, consider purchasing an entry-level instrument and plan to upgrade it at a later time. Pro Tip Once you have made a selection, you might want to try the technology more thoroughly before you commit to purchasing it. Having robust experimental proof can also help you make your case for the eventual purchase. To get experimental data from your lab's samples, you can work with a contract research organization, a collaborator, a vendor, or through a core facility. As with any other big purchases, once the financing is in place, the rest of the process is relatively straightforward. Most technologies require some form of installation, implementation, and training, all of which is typically provided by the vendor. Aside from occasional support and maintenance, your new instrument is ready to become an invaluable part of your workflow, providing valuable data that supports your research. To understand the total cost of investment, including both upfront and ongoing expenses, ask vendors what is included and excluded in their quote, and ensure they account for any daily maintenance costs.

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