Tech specs because it's
what's inside that matters
nanoDSF
Measurement parameters
Ratio: T
onset
, T
m
, E
a
, reversibility of unfolding
330 nm, 350 nm: T
m
Excitation: 280 nm
Concentration range 5 μg/mL - 250 mg/mL
Inflection point precision @ 75 °C ± 0.1 °C
Ratio precision/reproducibility 0.008
DLS
Measurement parameters T
size
, r
H
, PDI, k
D
, D
0
Laser wavelength 405 nm ± 5 nm
Concentration range 0.5 mg/mL for a 15 kDa protein, up to 40% w/v
Size resolution (DLS) Down to 0.5 nm
Backreflection
Measurement parameters T
turbidity
, reversibility of unfolding
Size resolution Larger than 12.5 nm radius
SLS
Measurement parameters T
scattering
, average scattering intensity, molecular weight, B
22
Measurement accuracy ≤ 10% molecular weight
Technology Specifications