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While biologics are derived from natural cellular
byproducts, it is generally neither cost- nor time-
efficient to extract the biologic from its source.
Where do Biologics come from?
Increasing the efficacy and
safety of biological therapeutics
is a central part of biologics
research.
Once a byproduct demonstrates potential value as a
therapeutic, the next step is to find ways to produce it cost-
effectively in vitro. This o en involves recombinant protein
expression, extraction, and purification. It may also involve
modifying the native protein sequence in order to improve
its expression rate, enzymatic efficiency, target affinity, or
long-term stability. These are crucial considerations that
can significantly improve the return on investment in the
development of a biologic.
