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The biologics researcher's guide to DLS

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Page 12 of 63

Now that we see why biologics are so important, and have gotten a taste of how DLS can help with stability monitoring, let's get into the science that drives it. DLS is a robust technique that gives you a lot of information about your biological candidates through all stages of your project workflow. It is considered to be a non-destructive and non-invasive measurement because it does not transfer energy to the sample and therefore does not alter the measurement. It's important to understand where the information comes from, and how the physical phenomena of scattered light can be transformed into valuable data for your work. Let's start with the theory behind DLS to give the basics of how light scattering works. The science behind DLS 2 13

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