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On the industry side of the research spectrum, binding
affinity is a useful metric during the earliest parts of the drug
development process when scientists are screening for
any compounds that interact with their target of interest.
Beginning with a large library of compounds or ligands,
industry scientists begin the screening process by identifying
which ones bind to the target protein, and then continue with
an increasingly smaller pool of compound candidates. A er
they complete much of their pre-clinical work, researchers
may measure binding affinity to determine and rank various
compounds' binding affinities for the target protein as an
indicator of potency of a possible drug candidate.
QUALITY COUNTS
When it comes to measuring binding affinity, or performing
any other experiment, for that matter, the quality of your
results will depend on the quality of the source material.
If you don't have any data on the quality of your source
material, the experiment is less likely to succeed.
