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Analyzing binding affinity can get complicated, you may
even need to consider adopting multiple technologies to
tackle your research. You could, for example, use a faster
technology that requires less sample to filter out 80% of
the molecules in your sample, and then use a slow, more
complex method to further study the remaining 20%.
The approach of using a faster, less complicated
technology will save you time, effort and money and
allow you to focus on the most relevant targets that
will further your research.
Several vendors offer technologies for measuring binding
affinity, and you can find most of the information about
their product offerings on their websites or in sales
collateral such as catalogs, brochures, and videos.
You can help yourself answer fundamental questions
about the features of the platform you are considering
by browsing the product specifications and features,
such as whether or not the instrument and so ware are
user-friendly, the size of the system's footprint, and what
consumables are required for its use.
Although this information will certainly help, it may not
answer all of your questions. Therefore, you may need to
contact the vendor. Before you do that, you may want to
VENDORS (ALPHA ORDER)
ForteBio
www.fortebio.com
ForteBio makes Octet and BLItz, instruments
for BioLayer Interferometry
GE Healthcare Life Sciences
www.proteins.gelifesciences.com
The Biacore Series from GE uses Surface
Plasmon Resonance
Malvern Instruments
www.malverninstruments.com
Malvern's MicroCal instruments enable
Isothermal Titration Calorimetry
NanoTemper Technologies
www.nanotempertech.com
NanoTemper offers Monolith, a series of
products for MicroScale Thermophoresis
How do I
evaluate vendors?
