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NT-MO-32-01
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References
1. Dominguez et al., p38 MAP kinase inhibitors: many are made, but
few are chosen. Curr Opin Drug Discov Devel. 2005 Jul;8(4):421-30.
2. Davis et al., Specificity and mechanism of action of some
commonly used protein kinase inhibitors. Biochem J. 2000 Oct
1;351(Pt 1):95-105.
3. Saxena et al., Competitive Assay Approach: Binding of Small
Molecules to the Active Form of p38. Application Note NT-MO-003
(2011).
4. Tschammer et al., One-step, purification-free and site-specific
labeling of polyhistidine-tagged proteins for MST. Application Note
NT-MO-29 (2016).
5. Cuenda et al., SB 203580 is a specific inhibitor of a MAP kinase
homologue which is stimulated by cellular stresses and
interleukin-1. 1995 FEBS Lett 229-233.