4
7 Stehling, O. & Lill, R. The role of mitochondria in
cellular iron-sulfur protein biogenesis: mechanisms,
connected processes, and diseases. Cold Spring
Harbor perspectives in biology 5, a011312,
doi:10.1101/cshperspect.a011312 (2013).
8 Beilschmidt, L. K. & Puccio, H. M. Mammalian Fe-S
cluster biogenesis and its implication in disease.
Biochimie, doi:10.1016/j.biochi.2014.01.009 (2014).
9 Tsai, C. L. & Barondeau, D. P. Human frataxin is an
allosteric switch that activates the Fe-S cluster
biosynthetic complex. Biochemistry 49, 9132-9139,
doi:10.1021/bi1013062 (2010).
10 Shi, Y., Ghosh, M., Kovtunovych, G., Crooks, D. R.
& Rouault, T. A. Both human ferredoxins 1 and 2
and ferredoxin reductase are important for iron-
sulfur cluster biogenesis. Biochimica et biophysica
acta 1823, 484-492,
doi:10.1016/j.bbamcr.2011.11.002 (2012).
11 Zheng, L., Cash, V. L., Flint, D. H. & Dean, D. R.
Assembly of iron-sulfur clusters. Identification of an
iscSUA-hscBA-fdx gene cluster from Azotobacter
vinelandii. J. Biol. Chem. 273, 13264-13272.
(1998).
12 Tokumoto, U. & Takahashi, Y. Genetic Analysis of
the isc Operon in Escherichia coli Involved in the
Biogenesis of Cellular Iron-Sulfur Proteins. J.
Biochem. (Tokyo) 130, 63-71. (2001)
13 Kim, J. H., Frederick, R. O., Reinen, N. M., Troupis,
A. T. & Markley, J. L. [2Fe-2S]-ferredoxin binds
directly to cysteine desulfurase and supplies an
electron for iron-sulfur cluster assembly but is
displaced by the scaffold protein or bacterial
frataxin. J Am Chem Soc 135, 8117-8120,
doi:10.1021/ja401950a (2013).
14 Mühlenhoff, U., Richter, N., Pines, O., Pierik, A. J. &
Lill, R. Specialized function of yeast Isa1 and Isa2
proteins in the maturation of mitochondrial [4Fe-4S]
proteins. J Biol Chem 286, 41205-41216,
doi:10.1074/jbc.M111.296152 (2011).
15 Wienken, C. J., Baaske, P., Rothbauer, U., Braun,
D. & Duhr, S. Protein-binding assays in biological
liquids using microscale thermophoresis. Nat
Commun 1, 100, doi:10.1038/ncomms1093 (2010).
16 Gerber, J., Neumann, K., Prohl, C., Mühlenhoff, U.
& Lill, R. The yeast scaffold proteins Isu1p and
Isu2p are required inside mitochondria for
maturation of cytosolic Fe/S proteins. Mol. Cell Biol.
24, 4848-4857. (2004).
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