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Once considered merely a passive link between proteins that matter, Grb2 – pronounced “grab2” – actually lives up to its nickname with its controlling grip on an important cell signaling pathway, scientists at The University of Texas MD Anderson Cancer Center report in the June 22 issue of Cell. Click here to read the complete MD Anderson press release.

Researchers around John E. Ladbury at the MD Anderson Cancer Center in Houston used their Monolith to detect and quantify the dimerization of the protein Grb2. Oligomerizations, that are typically very difficult to detect, are straight forward to analyze with MST, due to its low concentration needs and high sensitivity. Click here for the original publication.