Stefanie Kall

  • 5 considerations for buffer optimization during biologics pre-formulation

    5 considerations for buffer optimization during biologics pre-formulation

    Formulation development is a long, ongoing process during a candidate’s lifecycle. Broadly, it’s segmented into three categories: pre-formulation, formulation, and process development. The work of...

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  • 5 types of formulation excipients and how they impact biologics stability

    5 types of formulation excipients and how they impact biologics stability

    For pre-formulations researchers looking to find buffers that stabilize early development biologic products, buffer optimization goes beyond the pH and salt concentration of the solution....

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  • Get predictive insight into your ADC’s stability with these 3 experiments

    Get predictive insight into your ADC’s stability with these 3 experiments

    When developing ADCs, there are some strategies for protein assessment that will help mitigate the risk of destabilizing the final product during early development, particularly when optimizing...

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  • 5 biologics conferences you won’t want to miss in 2024

    5 biologics conferences you won’t want to miss in 2024

    Use this list of crowd-sourced favorites to kick-start your 2024 biologics conference plans. Find out when and where each conference takes place, who will be there, which topics are covered, and...

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  • De-risk your ADC development process with these stability considerations

    De-risk your ADC development process with these stability considerations

    Antibody-drug conjugates, or ADCs, are revolutionary therapeutics that represent a growing proportion of the biologics market. They combine the targeting power of a monoclonal antibody, which is...

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  • How do you get reproducible data from protein characterization experiments? Try following this DIN SPEC

    How do you get reproducible data from protein characterization experiments? Try following this DIN SPEC

    Reproducibility is a key tenet of scientific research, but many pharma groups have projects that collaborate across different sites or that rely on materials prepared by other specialist...

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  • 5 formulation changes you can evaluate with DLS to increase your biologics candidates' success

    5 formulation changes you can evaluate with DLS to increase your biologics candidates' success

    Biologics researchers are deeply concerned with formulation. Formulation typically refers to the final development of a deliverable, biologically derived molecule (such as a protein, peptide,...

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  • 5 experiments in biologics that can be improved with dynamic light scattering

    5 experiments in biologics that can be improved with dynamic light scattering

    Biologics, which are drugs and treatments derived from natural products, undergo a long development process before they reach the clinic. When you invest a lot of time and money in the process to...

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  • NanoTemper named one of Germany’s most innovative companies in 2021 by Capital

    NanoTemper named one of Germany’s most innovative companies in 2021 by Capital

    For the second year in a row, NanoTemper was named one of the most innovative companies in Germany by Capital magazine. A five out of five star distinction placed NanoTemper in the ranking’s top...

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  • The NanoTemper Story – Chapter 6: The Prometheus Panta

    The NanoTemper Story – Chapter 6: The Prometheus Panta

    In keeping with the Greek-based traditions of naming conventions, this instrument was dubbed the Prometheus Panta. Panta is a Greek term meaning “all” or “whole.” It was chosen because the...

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  • The NanoTemper Story – Chapter 5: The Dianthus

    The NanoTemper Story – Chapter 5: The Dianthus

    Adapting a technology to a completely different vessel is no easy task. Ten years after its inception, NanoTemper was a much larger company than it had been when they first started brainstorming...

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  • The NanoTemper Story – Chapter 4: The Tycho

    The NanoTemper Story – Chapter 4: The Tycho

    The Tycho was developed to help protein researchers better understand how their proteins are behaving. The Prometheus is great for advanced biophysical characterization, but sometimes all a...

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  • The NanoTemper Story – Chapter 3: The Prometheus

    The NanoTemper Story – Chapter 3: The Prometheus

    In its short history, the Prometheus has become the gold standard in protein characterization. Researchers around the world rely on the precise data obtained from this instrument. The story of the...

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  • The NanoTemper Story – Chapter 2: The Monolith

    The NanoTemper Story – Chapter 2: The Monolith

    Our CEOs, truly believed the Monolith would go on to change how scientists measured biophysical interactions. Their dedication to the technology helped recruit others to their cause, including...

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  • The NanoTemper Story – Chapter 1: The Founding

    The NanoTemper Story – Chapter 1: The Founding

    As PhD students in Munich, Nanotemper's founders Philipp Baaske and Stefan Duhr didn’t start their doctorates with the plan to launch a world-wide company that provides innovative instrumentation...

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  • How to export your data and set export templates in PR.Stability Analysis software

    How to export your data and set export templates in PR.Stability Analysis software

    Welcome to our next lesson from the Application Academy, where we will turn to PR.Stability Analysis software to expedite data processing and make it easy to pick out the data most relevant to you.

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  • How to get more out of your Prometheus data using Key Parameters in PR.Stability Analysis

    How to get more out of your Prometheus data using Key Parameters in PR.Stability Analysis

    PR.Stability Analysis offers a great feature to dramatically reduce the amount of time you spend processing your Prometheus data. With Key Parameters, it is possible to quickly and reliably...

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  • Compare your datasets with ease using percent similarity profiles in PR.Stability Analysis software

    Compare your datasets with ease using percent similarity profiles in PR.Stability Analysis software

    Whether you’re creating new buffer formulations, developing biosimilars, or comparing mutants of a protein of interest, Percent Similarity is a fast and easy way to evaluate how your changes have...

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  • Zoom in on your results using Regions of Interest in PR.Stability Analysis software

    Zoom in on your results using Regions of Interest in PR.Stability Analysis software

    PR.Stability Analysis software has a great new feature—Region of Interest—to help you develop that much-needed confidence in your conclusions. This feature enables you to focus only on the portion...

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  • Personalize your data by adding and removing markers in your datasets using PR.Stability Analysis software

    Personalize your data by adding and removing markers in your datasets using PR.Stability Analysis software

    When looking at large data sets, it is not easy to go through each individual unfolding curve looking for variations. Thus, researchers need parameters that can act as a quick measure of how...

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